Lee Meng, Huang Wen-Yi, Weng Hsu-Huei, Lee Jiann-Der, Lee Tsong-Hai
Department of Neurology, Chia-Yi branch, Chang Gung University College of Medicine, Tao-Yuan, Taiwan.
Eur Neurol. 2007;58(1):44-8. doi: 10.1159/000102166. Epub 2007 May 4.
Prior studies have been conducted in very old white and black patients. However, stroke in very old Asians has not been studied.
This study retrospectively reviewed the records of first-ever ischemic stroke patients admitted to the Chiayi Chang Gung Memorial Hospital in the middle part of Taiwan from January 2002 to December 2005. Clinical features, stroke subtypes, risk factors, acute ward mortality, length of acute ward stay, medical complications and medication for secondary stroke prevention at discharge were compared in 2 groups of first-ever ischemic stroke patients (one > or =80 and the other <80 years old).
Aged patients (> or =80 years old) had a higher proportion of conscious impairment at admission, a longer acute ward stay, a higher incidence of total anterior circulation infarct and a lower frequency of lacunar infarct, more frequent atrial fibrillation and less frequent diabetes mellitus, hyperlipidemia and smoking habits, and a higher incidence of pneumonia, urinary tract infection and upper gastrointestinal bleeding.
Understanding the risk factors and medical complications in very old stroke patients may help improve the stroke prevention strategy and the quality of stroke patient management.
既往研究针对的是高龄白种人和黑种人患者。然而，高龄亚洲人中风情况尚未得到研究。
本研究回顾性分析了2002年1月至2005年12月期间入住台湾中部嘉义长庚纪念医院的首次缺血性中风患者的病历。比较了两组首次缺血性中风患者（一组年龄≥80岁，另一组年龄<80岁）的临床特征、中风亚型、危险因素、急性病房死亡率、急性病房住院时间、医疗并发症以及出院时二级中风预防用药情况。
高龄患者（≥80岁）入院时意识障碍比例更高、急性病房住院时间更长、完全前循环梗死发生率更高、腔隙性梗死发生率更低、房颤更常见、糖尿病、高脂血症和吸烟习惯更不常见，且肺炎、尿路感染和上消化道出血发生率更高。
了解高龄中风患者的危险因素和医疗并发症可能有助于改进中风预防策略及提高中风患者管理质量。
