Nesti Claudia, Pasquali Livia, Vaglini Francesca, Siciliano Gabriele, Murri Luigi
CUCCS (Center for the Clinical Use of Stem Cells) and Department of Neurosciences, Section of Neurology, University of Pisa, Via Roma 67, Pisa, 56126, Italy.
Biosci Rep. 2007 Jun;27(1-3):165-71. doi: 10.1007/s10540-007-9044-1.
This mini-review summarizes the current literature on the role of mitochondrial DNA mutations and mitochondrial metabolism in stem cell biology. The possible uses of stem cells as a therapeutic tool in mitochondrial disorders are also reported.
本综述总结了当前关于线粒体DNA突变和线粒体代谢在干细胞生物学中作用的文献。还报道了干细胞作为线粒体疾病治疗工具的可能用途。