Licht Rasmus Wentzer, Straarup Krista Nielsen
Arhus Universitetshospital, Klinik for Mani og Depression, Risskov.
Ugeskr Laeger. 2007 Apr 16;169(16):1453-5.
Due to the episodic nature of affective disorders, treatments that prevent relapses/recurrences have a high priority. The number of long-term studies is scarce, but for moderate and severe cases of recurrent depression and for most cases of bipolar disorder, there is enough evidence to recommend various psychological interventions in combination with long-term pharmacotherapy (mainly antidepressants for recurrent depression and mainly lithium for bipolar disorder). Even though none of the treatments cause dramatic risk reduction, it is often possible to improve the individual prognosis through integrated long-term management by specialized teams.
由于情感障碍具有发作性,预防复发的治疗具有高度优先性。长期研究数量稀少,但对于复发性抑郁症的中重度病例以及大多数双相情感障碍病例,有足够证据推荐将各种心理干预与长期药物治疗相结合(复发性抑郁症主要使用抗抑郁药,双相情感障碍主要使用锂盐)。尽管没有哪种治疗能显著降低风险,但通过专业团队的综合长期管理,往往有可能改善个体预后。