Andersen Grethe, Brandt-Christensen Anne Mette, Nilsson Flemming Mørkeberg
Arhus Universitetshospital, Arhus Sygehus, Neurologisk Afdeling F, Arhus C.
Ugeskr Laeger. 2007 Apr 16;169(16):1467-9.
Depression frequently accompanies neurological disorders. Depressive symptoms have specific characteristics depending on the type of cerebral lesion, comorbidity and psychosocial impact. Difficulties in distinguishing mental symptoms from those caused by neurological damage partly explain the fact that depression is still under-diagnosed. Depression has a major negative impact on the quality of life and increases patients dependency on relatives. Evidence-based guidelines for treatment are very sparse and there is an urgent need for large-scale controlled trials.
抑郁症常与神经疾病相伴。抑郁症状因脑损伤类型、合并症及社会心理影响而具有特定特征。难以区分精神症状与神经损伤所致症状，这在一定程度上解释了抑郁症仍诊断不足的现状。抑郁症对生活质量有重大负面影响，并增加患者对亲属的依赖。基于证据的治疗指南非常稀少，迫切需要进行大规模对照试验。
