计算机调制型血液透析（CMP-HD）期间的液体转移

Fluid-shift during computer-modulated profile hemodialysis (CMP-HD).

作者信息

Keuchel M, Dittmar A, Saure B, Laage C, Ebel H, Lange H

机构信息

Department of Nephrology, Philipps-University of Marburg, Germany.

出版信息

Int J Artif Organs. 1991 Oct;14(10):630-3.

PMID:1748530

Abstract

Computer-modulated profile hemodialysis was examined for patients' comfort and fluid-shift. Fifteen patients were studied after two weeks of dialysis with each of the following profiles: A): constant ultrafiltration (UF) and dialysate sodium (138 mmol/l); B): decreasing UF; C): decreasing UF and decreasing high dialysate sodium (starting 10% above serum-sodium, with a gradual reduction to 138 mmol/l in the fourth hour). Patients with a calculated increase of intracellular volume (ICV) during dialysis had more complaints after dialysis than the others. ICV decreased in all patients with low serum-sodium (less than 136 mmol/l) during all profiles, whereas in patients with higher sodium, only profile C led to a decrease of ICV. However, interdialytic weight gain increased about 75% in patients with low serum-sodium under profile C. The sodium profile could help in preventing imbalance without side effects in patients with high sodium.

摘要

对计算机调节的血液透析曲线进行了研究，以了解患者的舒适度和液体转移情况。对15名患者在使用以下每种透析曲线进行两周透析后进行了研究：A）：恒定超滤（UF）和透析液钠（138 mmol/L）；B）：逐渐减少超滤；C）：逐渐减少超滤并降低高透析液钠（开始时比血清钠高10%，在第四小时逐渐降至138 mmol/L）。透析期间计算得出细胞内体积（ICV）增加的患者透析后比其他患者有更多不适。在所有透析曲线下，血清钠低（低于136 mmol/L）的所有患者ICV均降低，而血清钠较高的患者中，只有曲线C导致ICV降低。然而，在曲线C下血清钠低的患者透析间期体重增加约75%。钠曲线有助于预防高钠患者出现失衡且无副作用。