Werner J A, Lippert B M, Schmidt D, Rudert H
Klinik für Hals-, Nasen-, Ohrenheikunde, Kopf- und Halschirurgie, Universität Kiel.
HNO. 1991 Oct;39(10):405-9.
A total of 111 cases of laryngeal plasmacytoma have now been reported. The disease may present either as a primary extramedullary plasmacytoma (n = 90) or as a metastasis of a multiple myeloma (n = 21). The distinction between these two types is very important in therapy and prognosis. We report a subglottic plasmacytoma in a 48-year-old woman. Investigations showed bone marrow infiltration, osteolysis and light chain expression in serum, indicating generalized disease. Therefore polychemotherapy was given, during which complete macroscopic and microscopic regression of the laryngeal plasmacytoma was observed. However, 14 months later, the patient died of renal failure due to systemic progression of the multiple myeloma.
目前已报道了111例喉浆细胞瘤病例。该疾病可表现为原发性髓外浆细胞瘤（90例）或多发性骨髓瘤转移（21例）。这两种类型的区分在治疗和预后方面非常重要。我们报告了一例48岁女性的声门下浆细胞瘤。检查显示骨髓浸润、骨质溶解以及血清轻链表达，提示疾病已全身性扩散。因此给予了多药化疗，在此期间观察到喉浆细胞瘤在宏观和微观层面均完全消退。然而，14个月后，患者因多发性骨髓瘤的全身性进展死于肾衰竭。
