Department of Otolaryngology and Head and Neck Surgery, St Johns Medical College and Hospital, Bangalore, India.
J Voice. 2009 Nov;23(6):735-8. doi: 10.1016/j.jvoice.2008.03.009. Epub 2008 Jul 10.
Plasma cell myeloma, the most common plasma cell neoplasm, is characterized by the presence of multiple lesions in the bone marrow. A single isolated lesion may occur either in bone (solitary plasmacytoma of bone) or in soft tissue (extramedullary plasmacytoma). Most cases of extramedullary plasmacytoma occur in the head and neck region. The diagnosis is established by histopathology and immunohistochemistry. A detailed evaluation for lesions at other sites is recommended as extramedullary plasmacytoma treated by radiation therapy has better survival rates than plasma cell myeloma, which is treated by chemotherapy. A case of plasmacytoma of the larynx is presented highlighting clinical and histological features with a review of literature.
浆细胞瘤，最常见的浆细胞肿瘤，其特征是骨髓中有多个病变。单个孤立的病变可能发生在骨骼（孤立性骨浆细胞瘤）或软组织中（髓外浆细胞瘤）。大多数髓外浆细胞瘤发生在头颈部。诊断通过组织病理学和免疫组织化学建立。建议对其他部位的病变进行详细评估，因为接受放射治疗的髓外浆细胞瘤的生存率优于接受化疗的浆细胞骨髓瘤。本文报告了一例喉浆细胞瘤病例，重点介绍了其临床和组织学特征，并复习了文献。
