Hirashima Yoshinori, Kitajima Kazuaki, Sugi Saori, Kagawa Koichi, Murakami Kazunari, Fujioka Toshio, Kumamoto Toshihide
Third Department of Internal Medicine, Oita University Faculty of Medicine, Japan.
Nihon Shokakibyo Gakkai Zasshi. 2007 May;104(5):660-5.
A 75-year-old man was admitted to our hospital with the chief complaint of a choking feeling around the esophagus. Laboratory examinations revealed eosinophilia, and high levels of serum immunoglobulin (Ig) E. A computed tomography scan (CT) showed wall thickening of the esophagus and terminal ileum, and ascites around the liver. An endoscopic examination revealed mild mucosal edema in the esophagus, stomach, and small intestine. Biopsy specimens showed diffuse eosinophilic infiltration in the mucosa. We therefore diagnosed eosinophilic gastroenteritis. Oral prednisolone relieved clinical conditions and the CT image improved. This case was considered valuable, because there have been few reports of eosinophilic esophagitis in Japan.
一名75岁男性因食管周围有哽噎感为主诉入院。实验室检查显示嗜酸性粒细胞增多以及血清免疫球蛋白(Ig)E水平升高。计算机断层扫描(CT)显示食管和回肠末端壁增厚,肝脏周围有腹水。内镜检查显示食管、胃和小肠有轻度黏膜水肿。活检标本显示黏膜有弥漫性嗜酸性粒细胞浸润。因此,我们诊断为嗜酸性粒细胞性胃肠炎。口服泼尼松龙使临床症状缓解,CT图像改善。该病例被认为很有价值,因为在日本嗜酸性粒细胞性食管炎的报道很少。