Miyata Ryo, Torimaru Hiromitsu, Shimaoka Shunji, Matsuda Akio, Tashiro Kotaro, Nioh Tatsuyuki, Tsukasa Koichiro, Nishimata Nobuaki, Kawabata Takuya, Imamura Takako, Nagata Yuko, Niihara Toru, Hori Masahide, Nishimata Yoshito, Tanaka Sadao, Nishimata Hiroto, Tokushige Muneharu
Department of Gastroenterology, Nanpuh Hospital.
Nihon Shokakibyo Gakkai Zasshi. 2011 Dec;108(12):2010-5.
We report the case of a 15-year-old Japanese boy with eosinophilic gastroenteritis. The patient complained of abdominal pain and watery diarrhea and had a history of allergic rhinitis. Laboratory data on admission showed leukocytosis with remarkable eosinophilia. Microscopic examination of the biopsied specimens taken from the esophagus, stomach, duodenum, lower ileum and colon showed eosinophilic infiltration. Especially in the lower esophagus, there was a ring-like discoloration with remarkable eosinophil infiltration. We diagnosed eosinophilic gastroenteritis and his clinical symptoms and eosinophilia improved following starting corticosteroid therapy. After 5 months therapy with prednisolone, discoloration of upper digestive tract disappeared. There have been no reports describing discoloration in the lower end of the esophagus seen by gastroscopy.
我们报告一例15岁日本男孩患嗜酸性粒细胞性胃肠炎的病例。该患者主诉腹痛和水样腹泻,并有过敏性鼻炎病史。入院时实验室检查显示白细胞增多并伴有显著的嗜酸性粒细胞增多。对取自食管、胃、十二指肠、回肠末端和结肠的活检标本进行显微镜检查,显示有嗜酸性粒细胞浸润。特别是在食管下段,有环状变色并伴有显著的嗜酸性粒细胞浸润。我们诊断为嗜酸性粒细胞性胃肠炎,在开始使用皮质类固醇治疗后,他的临床症状和嗜酸性粒细胞增多情况有所改善。使用泼尼松龙治疗5个月后,上消化道变色消失。尚无关于胃镜检查所见食管下端变色的报道。