Korpusik D, Ruzicka T
Hautklinik des Universitätsklinikums Düsseldorf, Moorenstrasse 5, 40225, Düsseldorf, Germany.
Hautarzt. 2007 Oct;58(10):870-81. doi: 10.1007/s00105-007-1295-z.
Lymphomatoid papulosis is a rare disease with a worldwide incidence of 1.2 to 1.9 per 1 million. It affects all age groups with a peak incidence between 30 and 40 years and an apparent male predominance. Occurrence in childhood has also been described. Both the etiology and pathogenesis of the disease are unknown. The clinical presentation is extremely variable and frequently uncharacteristic. A papulonodular eruption, characterized by self-healing skin lesions appearing in crops can often be seen, particularly on extremities. We report on 17 patients, including 2 children. By detailing 6 cases we point out the variable morphologic manifestations, the different courses of disease and therapeutic options.
淋巴瘤样丘疹病是一种罕见疾病，全球发病率为每100万人中有1.2至1.9例。它可发生于所有年龄组，发病高峰在30至40岁之间，且明显以男性居多。也有儿童发病的报道。该疾病的病因和发病机制均不明。临床表现极为多样，且常常不典型。通常可见丘疹结节性皮疹，其特征为成群出现的可自愈的皮肤损害，尤其多见于四肢。我们报告了17例患者，其中包括2名儿童。通过详细描述6例病例，我们指出了其形态学表现的多样性、疾病的不同病程及治疗选择。
