Amann P M, Megahed M
Klinik für Dermatologie und Allergologie, Universitätsklinikum Aachen, Pauwelsstr. 30, 52074 Aachen.
Hautarzt. 2011 Nov;62(11):807-9. doi: 10.1007/s00105-011-2245-3.
Lymphomatoid papulosis (LyP) is a rare cutaneous lymphoproliferative disorder that has malignant histologic features and a benign clinical course. LyP is classified according to the WHO/EORTC classification for cutaneous lymphoma as a CD30-positive lymphoproliferative disorder. Few previous reports have detailed features of LyP in pediatric and adolescent patients, but LyP very rarely presents in early childhood. A 2 1/2-year-old boy presented with a 1-year history of recurrent papular and nodular lesions on the face and trunk. Clinical and histopathologic criteria lead to the diagnosis lymphomatoid papulosis.
淋巴瘤样丘疹病(LyP)是一种罕见的皮肤淋巴增殖性疾病,具有恶性组织学特征但临床病程良性。根据世界卫生组织/欧洲肿瘤研究与治疗组织(WHO/EORTC)皮肤淋巴瘤分类,LyP被归类为CD30阳性淋巴增殖性疾病。以前很少有报告详细描述儿童和青少年患者LyP的特征,而且LyP在幼儿期非常罕见。一名2岁半男孩有1年面部和躯干反复出现丘疹和结节性病变的病史。临床和组织病理学标准导致淋巴瘤样丘疹病的诊断。