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中耳类癌肿瘤。

Carcinoid tumor of the middle ear.

作者信息

Isipradit Permsarp, Asawavichianginda Saowaros, Keelawat Somboon

机构信息

Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2007 Apr;90(4):805-8.

Abstract

The patient was a 32 year-old man who was first seen in 2003 for 2 years hearing loss. On otoscopic examination, a whitish mass could be observed through the intact tympanic membrane. High resolution computed tomography showed a tumor like lesion in the middle ear with no evidence of bone destruction. A tympanomastoidectomy was performed. Light microscopy showed fragments of cellular tissue in which both glandular and trabecular growth pattern could be identified Immunohistochemical examinations showed positive staining of the tumor cells for cytokeratin and chromogranin. The diagnosis of carcinoid tumor should be considered in all cases of adenomatous neoplasms of the middle ear and mastoid. Conservative surgical excision is the treatment of choice, and local recurrence following complete excision is uncommon.

摘要

该患者为一名32岁男性,2003年因听力损失2年首次就诊。耳镜检查时,透过完整的鼓膜可观察到一个白色肿物。高分辨率计算机断层扫描显示中耳有一个肿瘤样病变,无骨质破坏迹象。行鼓室乳突切除术。光镜检查显示细胞组织碎片,其中可识别出腺性和小梁状生长模式。免疫组化检查显示肿瘤细胞角蛋白和嗜铬粒蛋白染色呈阳性。中耳和乳突腺瘤性肿瘤的所有病例均应考虑类癌瘤的诊断。保守性手术切除是首选治疗方法,完整切除后局部复发并不常见。

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