Poussa Heikki, Strandberg Timo E, Tikkanen Ilkka, Kauhanen Petteri, Lepäntalo Mauri
Department of Surgery, University of Helsinki, Finland.
Scand Cardiovasc J. 2007 Jun;41(3):138-41. doi: 10.1080/14017430601187751.
Our aim was to investigate how dyslipidemia was diagnosed and treated in patients with peripheral artery disease (PAD) in a university vascular clinic.
Our analysis included all 1 843 PAD patients (median age 71 years, interquartile range 63-79, M/W 975/868) who attended the clinic in 2002-2003 either for diagnostic angiography or for revascularization. The charts of patients tested for dyslipidemia were reviewed closer.
Serum lipids were measured in only 214 PAD patients (11.6%). Of them 37.9% smoked, 59.8% had antihypertensive medication, 35.0% diabetes, and 30.8% a history of coronary heart disease. Mean serum cholesterol concentration was 4.5 mmol/l (SD 1.3), LDL-cholesterol 2.54 (0.48), HDL-cholesterol 1.25 (0.48), and triglycerides 1.62 (0.84). Only 40 patients (19.7%) were using statins, this was increased to 72 (33.6%) after clinic visit. Consequently, 50.0% and 53.2% met the current total cholesterol (<4.5 mmol/l) and LDL-cholesterol (<2.5 mmol/l) goals, respectively.
Dyslipidemia was highly under-diagnosed among PAD patients. Serum lipids were measured only in a minority and among them serum lipid values and the use of hypolipidemic drugs were not optimal according to guidelines.
我们的目的是调查在一所大学血管诊所中，外周动脉疾病（PAD）患者的血脂异常是如何被诊断和治疗的。
我们的分析纳入了2002年至2003年到该诊所就诊以进行诊断性血管造影或血管重建的所有1843例PAD患者（中位年龄71岁，四分位间距63 - 79岁，男性/女性975/868）。对接受血脂异常检测的患者病历进行了更仔细的审查。
仅214例（11.6%）PAD患者检测了血脂。其中37.9%吸烟，59.8%服用抗高血压药物，35.0%患有糖尿病，30.8%有冠心病史。平均血清胆固醇浓度为4.5 mmol/l（标准差1.3），低密度脂蛋白胆固醇2.54（0.48），高密度脂蛋白胆固醇1.25（0.48），甘油三酯1.62（0.84）。仅40例患者（19.7%）使用他汀类药物，门诊就诊后这一比例增至72例（33.6%）。因此，分别有50.0%和53.2%的患者达到了目前的总胆固醇（<4.5 mmol/l）和低密度脂蛋白胆固醇（<2.5 mmol/l）目标。
PAD患者中血脂异常的诊断严重不足。仅少数患者检测了血脂，且根据指南，其中血脂值和降脂药物的使用情况并不理想。
