Cloud-Hansen Karen A, Villiard Katrina M, Handelsman Jo, Carey Hannah V
Department of Plant Pathology, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.
J Am Assoc Lab Anim Sci. 2007 May;46(3):21-3.
Whether wild-caught animals used for biomedical research carry antibiotic-resistant bacteria is not well studied. Thirteen- lined ground squirrels (Spermophilus tridecemlineatus) are small mammals used to study hibernation. These animals are captured from the wild or are born in laboratory animal facilities to wild-caught mothers. Because microorganisms harbored by 13-lined ground squirrels may be pathogenic to their caretakers and other laboratory animals, learning more about antibiotic resistance in these animals could be useful. In this study, tetracycline- and chloramphenicol-resistant Morganella morganii and multidrug resistant Stenotrophomonas maltophilia were isolated from the ceca of four 13-lined ground squirrels. These findings support further study of antibiotic-resistant bacterial populations in wild-caught mammals used as laboratory models.
用于生物医学研究的野生捕获动物是否携带抗生素耐药菌尚未得到充分研究。十三条纹地松鼠(Spermophilus tridecemlineatus)是用于研究冬眠的小型哺乳动物。这些动物要么从野外捕获,要么在实验动物设施中由野外捕获的母兽所生。由于十三条纹地松鼠携带的微生物可能对其饲养员和其他实验动物具有致病性,因此更多地了解这些动物的抗生素耐药性可能会有所帮助。在本研究中,从四只十三条纹地松鼠的盲肠中分离出了耐四环素和氯霉素的摩根氏摩根菌以及多重耐药的嗜麦芽窄食单胞菌。这些发现支持对用作实验室模型的野生捕获哺乳动物中的抗生素耐药细菌群体进行进一步研究。