Bhat B V, Verma I C, Puri R K, Srinivasan S, Nalini P
Department of Paediatrics, Jawaharial Institute of Postgraduate Medical Education and Research, Pondicherry.
J Indian Med Assoc. 1991 Aug;89(8):224-7.
Clinical profile of pyogenic meningitis was studied in 256 cases over a period of 8 years. The male to female ratio was 1.46: 1 and 83.6% of the patients were less than 3 years of age. Fever, altered sensorium, refusal to feed, convulsions and vomiting were the common presenting symptoms. Six (2.3%) of them had subnormal temperature and the sensorium was normal in 12.5% of cases. Cerebrospinal fluid was clear in 9.4%, cell count was less than 100/cmm in 8.2%, sugar was more than 40 mg% in 24.2% and protein was less than 50 mg% in 12.5% of cases. Diplococcus pneumoniae was the commonest causative agent. The overall mortality was 30.5%. It is concluded that young children suffering from this disease may not have the typical features and one should have the highest suspicion to make an early diagnosis so that the morbidity and mortality from this condition can be reduced.
在8年期间对256例化脓性脑膜炎患者的临床资料进行了研究。男女比例为1.46:1，83.6%的患者年龄小于3岁。发热、意识改变、拒食、惊厥和呕吐是常见的首发症状。其中6例（2.3%）体温低于正常，12.5%的病例意识正常。9.4%的病例脑脊液清晰，8.2%的病例细胞计数低于100/cmm，24.2%的病例糖含量高于40mg%，12.5%的病例蛋白质含量低于50mg%。肺炎双球菌是最常见的病原体。总死亡率为30.5%。结论是患有这种疾病的幼儿可能没有典型特征，应高度怀疑以便早期诊断，从而降低该病的发病率和死亡率。
