Willers Craig, Partsalis Theo, Zheng Ming-Hao
Department of Orthopaedics, School of Pathology and Surgery, University of Western Australia, 2nd Floor, M-block, QEII Medical Centre, Nedlands, Perth, WA 6009, Australia.
Expert Rev Med Devices. 2007 May;4(3):373-92. doi: 10.1586/17434440.4.3.373.
This review discusses the current perspectives and practices regarding the treatment of articular cartilage injury. Specifically, the authors have delineated and examined articular cartilage repair techniques as either surgical procedures or manufactured products. Although both methodologies are used to treat articular cartilage injury, there are obvious advantages and disadvantages to the application of both, with the literature providing few recommendations on the most suitable regimen for the patient and surgeon. In recent times, cell-based tissue engineering products, predominantly autologous chondrocyte implantation, have been the subject of much research and have become clinically popular. Herein, we review the most used procedures and products in cartilage repair, compare and contrast their outcomes, and evaluate the issues that must be overcome in order to improve patient efficacy in the future.
本综述讨论了目前关于关节软骨损伤治疗的观点和实践。具体而言，作者已将关节软骨修复技术划分为外科手术或制成品并进行了研究。尽管这两种方法都用于治疗关节软骨损伤，但两者的应用都有明显的优缺点，而文献中很少有关于最适合患者和外科医生的治疗方案的建议。近年来，基于细胞的组织工程产品，主要是自体软骨细胞植入，一直是大量研究的主题，并在临床上受到欢迎。在此，我们回顾了软骨修复中最常用的手术和产品，比较和对比它们的结果，并评估为了在未来提高患者疗效而必须克服的问题。
