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罗宾·库姆斯:他的生平及其对血液学和输血医学的贡献。

Robin Coombs: his life and contribution to haematology and transfusion medicine.

作者信息

Pamphilon Derwood H, Scott Marion L

机构信息

Bristol Institute for Transfusion Sciences, National Blood Service, Southmead Road, Bristol BS10 5ND, UK.

出版信息

Br J Haematol. 2007 Jun;137(5):401-8. doi: 10.1111/j.1365-2141.2007.06531.x.

DOI:10.1111/j.1365-2141.2007.06531.x
PMID:17488485
Abstract

Robin Coombs was the last survivor of the distinguished group of immunologists that included Philip Gell, John Humphrey, John Marrack, Peter Medawar and Robert White and who were responsible for the renaissance of British Immunology after the Second World War. He is best remembered for describing the antiglobulin test that bears his name. The antiglobulin test revolutionised the diagnosis of haemolytic diseases and the compatibility testing of blood for transfusion. In all, Coombs authored over 200 scientific papers. Haemagglutination reactions became widely used in the diagnosis of a range of infectious agents. Together with Philip Gell, he devised the classification of allergic reactions; these were published in the textbook "Clinical Aspects of Immunology", which he and Gell first edited in 1963 and which became the leading textbook on medical immunology. Robin Coombs was also one of the founders of the British Society for Immunology.

摘要

罗宾·库姆斯是杰出免疫学家群体中的最后一位幸存者,这个群体包括菲利普·盖尔、约翰·汉弗莱、约翰·马勒克、彼得·梅达瓦尔和罗伯特·怀特,他们在二战后推动了英国免疫学的复兴。他最为人铭记的是描述了以他名字命名的抗球蛋白试验。抗球蛋白试验彻底改变了溶血性疾病的诊断以及输血用血的相容性检测。库姆斯总共撰写了200多篇科学论文。血凝反应在一系列传染病原体的诊断中得到广泛应用。他与菲利普·盖尔一起设计了过敏反应的分类;这些内容发表在教科书《免疫学临床方面》中,该书由他和盖尔于1963年首次编辑,成为医学免疫学的权威教科书。罗宾·库姆斯也是英国免疫学会的创始人之一。

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