靶向脂肪预防糖尿病。
Targeting fat to prevent diabetes.
作者信息
Sethi Jaswinder K, Vidal-Puig Antonio J
机构信息
Department of Clinical Biochemistry, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QR, UK.
出版信息
Cell Metab. 2007 May;5(5):323-5. doi: 10.1016/j.cmet.2007.04.006.
Abstract
An emerging view is that obesity causes metabolic problems when adipose tissue fails to meet the increased demands for fat storage. A study in this issue of Cell Metabolism (Waki et al., 2007) has identified harmine as a proadipogenic small molecule that promotes energy expenditure in white adipose tissue and delays the onset of obesity-associated diabetes.
摘要
一种新出现的观点认为，当脂肪组织无法满足增加的脂肪储存需求时，肥胖就会引发代谢问题。发表于本期《细胞代谢》（Waki等人，2007年）的一项研究已确定 harmine 是一种促脂肪生成的小分子，它能促进白色脂肪组织中的能量消耗，并延缓肥胖相关糖尿病的发病。
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