Jauréguiberry Stéphane, Ansart Séverine, Perez Lucia, Danis Martin, Bricaire François, Caumes Eric
Department of Infectious and Tropical Disease, Hôpital Tenon, Assistance Publique Hopitaux de Paris, Paris, France.
Am J Trop Med Hyg. 2007 May;76(5):964-6.
Encephalitis and focal neurologic deficits can occur during the acute phase of schistosomiasis. We report two cases in which cerebral imaging showed cerebral vasculitis located in arterial junctional territories. These neurologic complications may be caused by eosinophil-mediated toxicity. Immediate treatment should consist of corticosteroids rather than specific antischistosomal drugs, which may aggravate the disorders.
脑炎和局灶性神经功能缺损可在血吸虫病急性期发生。我们报告两例病例,其脑部影像学显示脑动脉交界区血管炎。这些神经并发症可能由嗜酸性粒细胞介导的毒性引起。立即治疗应使用皮质类固醇而非特异性抗血吸虫药物,后者可能会加重病情。