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癌症与衰老的关联:一项研究议程。

The cancer aging interface: a research agenda.

作者信息

Cohen Harvey Jay

机构信息

Department of Medicine, Center for the Study of Aging and Human Development, Duke University Medical Center, Geriatric Research Education and Clinical Center, Veterans Affairs Medical Center, Durham, NC 27710, USA.

出版信息

J Clin Oncol. 2007 May 10;25(14):1945-8. doi: 10.1200/JCO.2007.10.6807.

DOI:10.1200/JCO.2007.10.6807
PMID:17488995
Abstract

There are substantial knowledge gaps in our understanding of the relationships between cancer and aging. These include areas of basic biology, societal aspects, and clinical aspects. Recommendations for research agendas in each of these areas are offered. In addition, the need for training investigators to work at this interface is addressed.

摘要

在我们对癌症与衰老之间关系的理解上存在重大知识空白。这些空白涵盖基础生物学、社会层面和临床层面等领域。本文针对这些领域中的每一个都提出了研究议程建议。此外,还讨论了培训研究人员在这一交叉领域开展工作的必要性。

相似文献

1
The cancer aging interface: a research agenda.癌症与衰老的关联:一项研究议程。
J Clin Oncol. 2007 May 10;25(14):1945-8. doi: 10.1200/JCO.2007.10.6807.
2
An agenda for clinical research in geriatrics.老年病临床研究议程。
Cancer. 1997 Oct 1;80(7):1294-301.
3
The biology of aging: the current research agenda.衰老生物学:当前的研究议程。
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The 2008 American Federation For Aging Annual Research Conference: aging and cancer: two sides of the same coin?2008年美国老年医学会年度研究会议:衰老与癌症:同一枚硬币的两面?
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Providing research participants with findings from completed cancer-related clinical trials: not quite as simple as it sounds.向研究参与者提供已完成的癌症相关临床试验的结果:这并非听起来那么简单。
Cancer. 2006 Apr 1;106(7):1421-4. doi: 10.1002/cncr.21757.
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Providing research participants with findings from completed cancer-related clinical trials: not quite as simple as it sounds.向研究参与者提供已完成的癌症相关临床试验的结果:并非听起来那么简单。
Cancer. 2006 Sep 15;107(6):1419-20; author reply 1420. doi: 10.1002/cncr.22140.
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Under-representation of older adults in cancer registration trials: known problem, little progress.老年成年人在癌症登记试验中的代表性不足:已知问题,进展甚微。
J Clin Oncol. 2012 Jun 10;30(17):2036-8. doi: 10.1200/JCO.2012.41.6727. Epub 2012 Apr 30.

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Front Aging. 2023 Dec 4;4:1305922. doi: 10.3389/fragi.2023.1305922. eCollection 2023.
2
Cognitive function and discontinuation of adjuvant hormonal therapy in older breast cancer survivors: CALGB 369901 (Alliance).认知功能与老年乳腺癌幸存者辅助激素治疗的停药:CALGB 369901(Alliance)。
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Clin Interv Aging. 2016 Feb 3;11:111-25. doi: 10.2147/CIA.S65304. eCollection 2016.
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Proposing an Interdisciplinary, Communication-Focused Agenda for Cancer and Aging Researchers.为癌症与衰老研究人员提出一个以跨学科、沟通为重点的议程。
J Cancer Educ. 2016 Jun;31(2):218-20. doi: 10.1007/s13187-015-0822-3.
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A patient-centered research agenda for the care of the acutely ill older patient.一项以患者为中心的急性病老年患者护理研究议程。
J Hosp Med. 2015 May;10(5):318-27. doi: 10.1002/jhm.2356. Epub 2015 Apr 16.
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The SAKK cancer-specific geriatric assessment (C-SGA): a pilot study of a brief tool for clinical decision-making in older cancer patients.瑞士癌症研究协会癌症特异性老年评估(C-SGA):一项针对老年癌症患者临床决策简短工具的试点研究。
BMC Med Inform Decis Mak. 2013 Aug 23;13:93. doi: 10.1186/1472-6947-13-93.
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Age-associated gene expression in normal breast tissue mirrors qualitative age-at-incidence patterns for breast cancer.正常乳腺组织中的与年龄相关的基因表达反映了乳腺癌发病年龄的定性模式。
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Translation Requires Evidence: Does Cancer-Specific CGA Lead to Better Care and Outcomes?翻译需要证据:癌症特异性综合老年评估能否带来更好的护理和结局?
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