一只斯普拉格-道利大鼠出现雌雄同体现象。

Hermaphroditism in a Sprague-Dawley rat.

作者信息

Diters R W, Funk K A, Fang H, Durham S K, Mense M G

机构信息

Bristol-Myers Squibb Company, PO Box 4755, Syracuse, NY 13221, USA.

出版信息

Vet Pathol. 2007 May;44(3):418-20. doi: 10.1354/vp.44-3-418.

DOI:10.1354/vp.44-3-418

PMID:17491092

Abstract

A spontaneous case of unilateral true hermaphroditism was observed during the routine necropsy of a 9-week-old presumed female Sprague-Dawley rat on a repeat-dose toxicity study. There were no drug-related effects observed. True hermaphroditism is rare in rats, and despite the large numbers of rats examined annually, few cases are reported in the literature.

摘要

在一项重复给药毒性研究中，对一只9周龄、推测为雌性的斯普拉格-道利大鼠进行常规尸检时，发现了一例自发的单侧真性两性畸形病例。未观察到与药物相关的影响。真性两性畸形在大鼠中很少见，尽管每年检查大量大鼠，但文献报道的病例很少。