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通过互联网戒烟:一项关于互联网干预作为戒烟干预辅助治疗的随机临床试验。

Smoking cessation via the internet: a randomized clinical trial of an internet intervention as adjuvant treatment in a smoking cessation intervention.

作者信息

Japuntich Sandra J, Zehner Mark E, Smith Stevens S, Jorenby Douglas E, Valdez José A, Fiore Michael C, Baker Timothy B, Gustafson David H

机构信息

Center for Tobacco Research and Intervention, University of Wisconsin School of Medicine and Public Health, 1930 Monroe Street, Suite 200, Madison, WI 53711, USA.

出版信息

Nicotine Tob Res. 2006 Dec;8 Suppl 1:S59-67. doi: 10.1080/14622200601047900.

Abstract

Internet interventions for smoking cessation are ubiquitous. Yet, to date, there are few randomized clinical trials that gauge their efficacy. This study is a randomized clinical trial (N= 284, n= 140 in the treatment group, n= 144 in the control group) of an Internet smoking cessation intervention. Smokers were randomly assigned to receive either bupropion plus counseling alone, or bupropion and counseling in addition to 12 weeks of access to the Comprehensive Health Enhancement Support System for Smoking Cessation and Relapse Prevention (CHESS SCRP; a Web site which provided information on smoking cessation as well as support). We found that access to CHESS SCRP was not significantly related to abstinence at the end of the treatment period (OR= 1.13, 95% CI 0.66-2.62) or at 6 months postquit (OR= 1.48, 95% CI 0.66-2.62). However, the number of times participants used CHESS SCRP per week was related to abstinence at both end of treatment (OR= 1.79, 95% CI 1.25-2.56) and at the 6-month follow-up (OR= 1.59, 95% CI 1.06-2.38). Participants with access to CHESS SCRP logged in an average of 33.64 times (SD=30.76) over the 90-day period of access. Rates of CHESS SCRP use did not differ by ethnicity, level of education or gender (all p>.05). In sum, results suggest that participants used CHESS SCRP frequently, CHESS SCRP use was related to success, but the effects in general did not yield intergroup effects.

摘要

用于戒烟的互联网干预措施随处可见。然而,迄今为止,很少有随机临床试验来评估其效果。本研究是一项针对互联网戒烟干预措施的随机临床试验(N = 284,治疗组n = 140,对照组n = 144)。吸烟者被随机分配,要么仅接受安非他酮加咨询,要么在接受安非他酮和咨询的同时,还可在12周内访问戒烟与预防复吸综合健康强化支持系统(CHESS SCRP;一个提供戒烟信息及支持的网站)。我们发现,在治疗期结束时(OR = 1.13,95%可信区间0.66 - 2.62)或戒烟后6个月时(OR = 1.48,95%可信区间0.66 - 2.62),访问CHESS SCRP与戒烟并无显著关联。然而,参与者每周使用CHESS SCRP的次数与治疗结束时(OR = 1.79,95%可信区间1.25 - 2.56)及6个月随访时(OR = 1.59,95%可信区间1.06 - 2.38)的戒烟情况相关。在90天的访问期内,能够访问CHESS SCRP的参与者平均登录33.64次(标准差 = 30.76)。CHESS SCRP的使用频率在不同种族、教育程度或性别之间并无差异(所有p>0.05)。总之,结果表明参与者频繁使用CHESS SCRP,CHESS SCRP的使用与成功戒烟有关,但总体效果并未产生组间差异。

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