Etter Jean-François
Institute of Social and Preventive Medicine, University of Geneva, 1 rue Michel-Servet, CH-1211 Geneva 4, Switzerland.
J Med Internet Res. 2005 Mar 8;7(1):e2. doi: 10.2196/jmir.7.1.e2.
Online computer-tailored smoking cessation programs have not yet been compared directly.
To compare the efficacy of two Internet-based, computer-tailored smoking cessation programs.
Randomized controlled trial conducted in 2003-2004. Visitors to a smoking cessation website were randomly assigned to either an original online, interactive smoking cessation program or to a modified program. Both programs consisted of tailored, personalized counseling letters based on participants' characteristics, followed by monthly email reminders. The original program was based on psychological and addiction theory, and on preliminary research conducted in the same population. The modified program was shorter and contained more information on nicotine replacement therapy and nicotine dependence, and less information on health risks and coping strategies. In both programs, 1 month and 2 months after entering the study, participants were invited by email to answer the same tailoring questionnaire again in order to receive a second counseling letter. Participants in both programs obtained, on average, 1.2 feedback counseling letters over 2.5 months, and 84% received only 1 feedback letter. The outcome was self-reported smoking abstinence (no puff of tobacco in the previous 7 days), assessed 2.5 months after entry in the program. We report results from intention-to-treat (ITT) analyses, where all non-respondents at follow-up were counted as smokers.
The baseline questionnaire was answered by a total of 11969 current (74%) and former (26%) smokers, and the follow-up survey by 4237 people (35%). In an ITT analysis, abstinence rates in baseline current smokers were respectively 10.9% and 8.9% (odds ratio [OR]=1.24, 95% confidence interval [CI]1.08-1.43, P=.003) in the original and modified programs, and 25.2% and 15.7% (OR=1.81, CI 1.51-2.16, P<.001) in baseline former smokers. While we found statistically significant differences in quit rates in smokers in the contemplation stage favoring the original program (OR=1.54, CI 1.18-2.02, P=.002), no between-group differences in quit rates were observed in smokers in the precontemplation (OR=1.07, CI 0.36-3.14, P=.91) and preparation (OR=1.15, CI 0.97-1.37, P=.10) stages of change.
In smokers in the contemplation stage of change and in former smokers, the original program produced higher smoking abstinence rates than the modified program.
在线计算机定制戒烟项目尚未进行直接比较。
比较两个基于互联网的计算机定制戒烟项目的疗效。
于2003年至2004年进行随机对照试验。戒烟网站的访客被随机分配到一个原始的在线交互式戒烟项目或一个修改后的项目。两个项目均包括根据参与者特征定制的个性化咨询信件,随后是每月的电子邮件提醒。原始项目基于心理和成瘾理论以及在同一人群中进行的初步研究。修改后的项目较短,包含更多关于尼古丁替代疗法和尼古丁依赖的信息,而关于健康风险和应对策略的信息较少。在两个项目中,进入研究1个月和2个月后,通过电子邮件邀请参与者再次回答相同的定制问卷,以便收到第二封咨询信件。两个项目的参与者在2.5个月内平均获得1.2封反馈咨询信件,84%的参与者只收到1封反馈信件。结局指标为自我报告的戒烟情况(过去7天未吸一口烟),在进入项目2.5个月后进行评估。我们报告意向性分析(ITT)的结果,即所有随访时未回复者均计为吸烟者。
共有11969名当前吸烟者(74%)和既往吸烟者(26%)回答了基线问卷,4237人(35%)完成了随访调查。在ITT分析中,原始项目和修改后项目中基线当前吸烟者的戒烟率分别为10.9%和8.9%(优势比[OR]=1.24,95%置信区间[CI]1.08 - 1.43,P = 0.003),基线既往吸烟者的戒烟率分别为25.2%和15.7%(OR = 1.81,CI 1.51 - 2.16,P < 0.001)。虽然我们发现处于思考阶段的吸烟者中,原始项目的戒烟率在统计学上有显著差异(OR = 1.54,CI 1.18 - 2.02,P = 0.002),但在未思考阶段(OR = 1.07,CI 0.36 - 3.14,P = 0.91)和准备阶段(OR = 1.15,CI 0.97 - 1.37,P = 0.10)的吸烟者中,未观察到组间戒烟率差异。
对于处于思考阶段的吸烟者和既往吸烟者,原始项目的戒烟率高于修改后的项目。