Saenko V F, Cherviak P I, Shalimov S V, Khakimov P Ia
Klin Khir (1962). 1991(8):1-3.
Examined were 53 patients with dysplasia of the gastric mucosal epithelium revealed at endoscopic and histologic study. In detection of moderately pronounced dysplasia, the conservative treatment of the underlying disease with endoscopic and histologic control every 6 mos is indicated; in severe dysplasia--conservative treatment with dynamic control every 3 mos; in absence of positive dynamics of the dysplastic process within a year, or in suspected malignant transformation--the operative intervention, the volume of which is determined by spreading of the foci of dysplasia. The patients operated on for severe dysplasia of the gastric mucosal epithelium should be under continuous supervision.
对53例经内镜及组织学检查发现胃黏膜上皮发育异常的患者进行了检查。对于中度发育异常的检测,建议对基础疾病进行保守治疗,每6个月进行内镜及组织学检查;对于重度发育异常,每3个月进行动态控制的保守治疗;如果发育异常过程在一年内没有积极变化,或怀疑有恶变,则进行手术干预,手术范围由发育异常病灶的扩散情况决定。因胃黏膜上皮重度发育异常而接受手术的患者应接受持续监测。