Turk J, Kenda M, Kranjec I
Department of Cardiovascular Diseases, University Medical Centre, Ljubljana, Yugoslavia.
Klin Wochenschr. 1991 Sep 16;69(14):674-8. doi: 10.1007/BF01649430.
Malignant primary tumors of the pericardium are rare. The authors present two male patients, aged 44 and 67 years, not exposed to asbestos, who died from pericardial mesothelioma. Repeated evacuation of fluid from the pericardium due to cardiac tamponade failed to reveal the cause of pericarditis. In one case, the diagnosis was made on surgical exploration, and in the other, at autopsy. A significant difference between benign and malignant pericardial effusion was observed. In cases of pericardial mesothelioma, symptoms of epicardial involvement cannot be attributed solely to the hindered inflow and cardiac tamponade, but also to congestive heart failure due to myocardial infiltration. In one patient, temporary improvement was achieved, first by pronisone therapy and then by radiotherapy.
原发性恶性心包肿瘤很罕见。作者报告了两名男性患者，年龄分别为44岁和67岁，未接触过石棉，均死于心包间皮瘤。因心脏压塞反复进行心包穿刺引流，但未能明确心包炎的病因。其中1例经手术探查确诊，另1例经尸检确诊。观察到良性和恶性心包积液之间存在显著差异。在心包间皮瘤病例中，心外膜受累的症状不能仅归因于流入受阻和心脏压塞，还应归因于心肌浸润导致的充血性心力衰竭。在1例患者中，首先通过泼尼松治疗，然后通过放疗，病情暂时得到改善。
