• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

磷脂酶A2和C对鱿鱼（莱氏拟乌贼）巨轴突的穿透作用。

Penetration of phospholipases A2 and C into the squid (Loligo pealii) giant axon.

作者信息

Rosenberg P

出版信息

Experientia. 1975 Dec 15;31(12):1401-3. doi: 10.1007/BF01923210.

DOI:10.1007/BF01923210
PMID:174931
Abstract

Following 1 h exposure, the level of phospholipase A2 penetration into the axoplasm of the squid giant axon was 107 to 350% of that in the external media; corresponding values for phospholipase C were 18 to 31%. Phospholipases can therefore be used to study phospholipid function in axons since they can penetrate through connective tissue and Schwann cell to reach the axolemma.

摘要

暴露1小时后，磷脂酶A2进入鱿鱼巨大轴突轴浆的水平是外部介质中的107%至350%；磷脂酶C的相应值为18%至31%。因此，磷脂酶可用于研究轴突中的磷脂功能，因为它们可以穿透结缔组织和施万细胞到达轴膜。

相似文献

1
Penetration of phospholipases A2 and C into the squid (Loligo pealii) giant axon.磷脂酶A2和C对鱿鱼（莱氏拟乌贼）巨轴突的穿透作用。
Experientia. 1975 Dec 15;31(12):1401-3. doi: 10.1007/BF01923210.
2
Characterization of phospholipase A2 and acyltransferase activities in squid (Loligo pealei) axoplasm: comparison with enzyme activities in other neural tissues, axolemma and axoplasmic subfractions.枪乌贼（莱氏拟乌贼）轴浆中磷脂酶A2和酰基转移酶活性的表征：与其他神经组织、轴膜和轴浆亚组分中的酶活性比较
Neurochem Int. 1992 Dec;21(4):563-71. doi: 10.1016/0197-0186(92)90089-a.
3
Analysis of microtubules in isolated axoplasm from the squid giant axon.对鱿鱼巨大轴突分离出的轴质中微管的分析。
Methods Cell Biol. 2013;115:125-37. doi: 10.1016/B978-0-12-407757-7.00009-8.
4
Further studies on the nature of the excitable system in nerve. I. Voltage-induced axoplasm movement in squid axons. II. Penetration of surviving, excitable axons by proteases. III. Effects of proteases and of phospholipases on lobster giant axon resistance and capacity.关于神经中可兴奋系统性质的进一步研究。I. 枪乌贼轴突中电压诱导的轴浆运动。II. 蛋白酶对存活的可兴奋轴突的穿透作用。III. 蛋白酶和磷脂酶对龙虾巨轴突电阻和电容的影响。
J Gen Physiol. 1960 May;43(5):57-71. doi: 10.1085/jgp.43.5.57.
5
Fast axonal transport in isolated axoplasm from the squid giant axon.来自鱿鱼巨轴突的分离轴质中的快速轴突运输。
Methods Cell Biol. 2016;131:331-48. doi: 10.1016/bs.mcb.2015.07.004. Epub 2015 Sep 2.
6
Phospholipid synthesis in the squid giant axon: incorporation of lipid precursors.鱿鱼巨大轴突中的磷脂合成：脂质前体的掺入
J Neurochem. 1983 May;40(5):1293-9. doi: 10.1111/j.1471-4159.1983.tb13569.x.
7
Cell-to-cell transfer of glial proteins to the squid giant axon. The glia-neuron protein trnasfer hypothesis.胶质蛋白向鱿鱼巨轴突的细胞间转移。胶质-神经元蛋白转移假说。
J Cell Biol. 1977 Aug;74(2):501-23. doi: 10.1083/jcb.74.2.501.
8
Transfer of newly synthesized proteins from Schwann cells to the squid giant axon.新合成蛋白质从施万细胞向乌贼巨大轴突的转移。
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1188-92. doi: 10.1073/pnas.71.4.1188.
9
The cytochrome oxidase and succinic dehydrogenase contents of squid (Loligo pealii) axoplasm and other nervous tissues.鱿鱼（太平洋褶柔鱼）轴浆及其他神经组织中的细胞色素氧化酶和琥珀酸脱氢酶含量。
Biol Bull. 1950 Oct;99(2):356. doi: 10.1086/BBLv99n2p321.
10
Glial polypeptides transferred into the squid giant axon.转移至鱿鱼巨大轴突中的神经胶质多肽。
Brain Res. 1984 Dec 24;324(2):223-32. doi: 10.1016/0006-8993(84)90032-5.

引用本文的文献

1
Effects of Sr2+ and Mg2+ on the phospholipase A and the presynaptic neuromuscular blocking actions of beta-bungarotoxin, crotoxin and taipoxin.Sr2+和Mg2+对磷脂酶A以及β-银环蛇毒素、响尾蛇毒素和太攀蛇毒素的突触前神经肌肉阻断作用的影响。
Naunyn Schmiedebergs Arch Pharmacol. 1977 Sep;299(2):155-61. doi: 10.1007/BF00498557.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
EFFECTS OF VARIOUS POTASSIUM SALTS AND PROTEASES UPON EXCITABILITY OF INTRACELLULARLY PERFUSED SQUID GIANT AXONS.各种钾盐和蛋白酶对细胞内灌注枪乌贼巨轴突兴奋性的影响。
Proc Natl Acad Sci U S A. 1964 Sep;52(3):804-10. doi: 10.1073/pnas.52.3.804.
3
FACTORS IN VENOMS LEADING TO BLOCK OF AXONAL CONDUCTION BY CURARE.毒液中导致箭毒阻断轴突传导的因素。
Biochim Biophys Acta. 1963 Jul 23;75:116-28. doi: 10.1016/0006-3002(63)90585-7.
4
Demonstration of increased permeability as a factor in the effect of acetylcholine on the electrical activty of venom-treated axons.乙酰胆碱对经毒液处理的轴突电活动的影响中，通透性增加作为一个因素的证明。
J Gen Physiol. 1963 May;46(5):1065-73. doi: 10.1085/jgp.46.5.1065.
5
Phospholipase C determination by egg yolk turbidimetry.采用蛋黄比浊法测定磷脂酶C
Anal Biochem. 1963 Jan;5:37-46. doi: 10.1016/0003-2697(63)90055-1.
6
The estimation of phospholipase A activity in aqueous systems.水相体系中磷脂酶A活性的测定
Biochem J. 1960 Dec;77(3):526-34. doi: 10.1042/bj0770526.
7
A relation between non-esterified fatty acids in plasma and the metabolism of glucose.血浆中非酯化脂肪酸与葡萄糖代谢之间的关系。
J Clin Invest. 1956 Feb;35(2):150-4. doi: 10.1172/JCI103259.
8
Demonstration of phospholipid splitting as the factor responsible for increased permeability and block of axonal conduction induced by snake venom. II. Study on squid axons.证明磷脂分解是蛇毒诱导的通透性增加和轴突传导阻滞的原因。II. 对鱿鱼轴突的研究。
Biochim Biophys Acta. 1968 Mar 1;150(2):271-84. doi: 10.1016/0005-2736(68)90170-3.
9
The optical activity of plasma membranes and its modification by lysolecithin, phospholipase A and phospholipase C.质膜的旋光性及其被溶血卵磷脂、磷脂酶A和磷脂酶C的修饰作用。
Biochim Biophys Acta. 1969;183(3):405-16. doi: 10.1016/0005-2736(69)90155-2.
10
The action of phospholipases on the inner and outer surface of the squid giant axon membrane.磷脂酶对鱿鱼巨大轴突膜内外表面的作用。
J Physiol. 1972 Jan;220(1):73-86. doi: 10.1113/jphysiol.1972.sp009695.