Guez G, Gandar R, Schuy E, Knapstein P, Oertel G
Experientia. 1976 Jan 15;32(1):117-8. doi: 10.1007/BF01932657.
When free DHEA, its sulfatide, and sulfate were assayed in maternal plasma as well as in umbilical cord arterial and venous plasma, rather high concentrations were found in either fraction from cord arterial plasma, reflecting the fetal contribution not only of free DHEA and DHEA sulfate, but also of the lipophile steroid sulfatide. Since high DHEA levels were associated with elevated c-AMP concentrations, a certain interrelationship of both parameters is indicated. In the course of delivery, a rapid decrease of free estriol in maternal plasma was observed. Higher concentration of free estriol in umbilical venous plasma pointed at its placental biosynthesis from fetal precursors.
当对母体血浆以及脐动脉和脐静脉血浆中的游离脱氢表雄酮（DHEA）、其硫酸酯和硫酸盐进行检测时，发现脐动脉血浆中各组分的浓度相当高，这不仅反映了胎儿对游离DHEA和硫酸脱氢表雄酮的贡献，还反映了亲脂性甾体硫酸酯的贡献。由于高DHEA水平与c-AMP浓度升高相关，表明这两个参数之间存在一定的相互关系。在分娩过程中，观察到母体血浆中游离雌三醇迅速下降。脐静脉血浆中游离雌三醇浓度较高，表明其由胎儿前体物质经胎盘生物合成而来。
