Clark Sunday, Camargo Carlos A
Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, 326 Cambridge Street, Suite 410, Boston, MA 02114, USA.
Immunol Allergy Clin North Am. 2007 May;27(2):145-63, v. doi: 10.1016/j.iac.2007.03.002.
Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. Understanding the epidemiology of anaphylaxis has important implications for preventing anaphylaxis and managing patients. Unfortunately, estimates of the prevalence and incidence of anaphylaxis vary widely. Inconsistent definitions of anaphylaxis contribute to these divergent estimates. The implementation of a simple clinical definition to diagnose anaphylaxis not only would help in the management of patients but also would advance epidemiologic research on the distribution and determinants of this potentially life-threatening disease.
过敏反应是一种起病迅速的严重过敏反应，可能导致死亡。了解过敏反应的流行病学对于预防过敏反应和治疗患者具有重要意义。不幸的是，对过敏反应患病率和发病率的估计差异很大。过敏反应定义不一致导致了这些不同的估计。实施一个简单的临床定义来诊断过敏反应不仅有助于患者的治疗，还将推动对这种潜在危及生命疾病的分布和决定因素的流行病学研究。
