Ensina Luis Felipe, Min Taek Ki, Félix Mara Morelo Rocha, de Alcântara Carolina Tavares, Costa Célia
Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Federal University of São Paulo, São Paulo, Brazil.
Department of Pediatrics, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, South Korea.
Front Allergy. 2022 Apr 15;3:840999. doi: 10.3389/falgy.2022.840999. eCollection 2022.
Acute urticaria is a common condition that presents with wheals and/or angioedema. However, these symptoms are also frequent in anaphylaxis, a life-threatening reaction that should be immediately diagnosed and treated. In both, mast cells play a central role in the physiopathology. Causes and triggers of acute urticaria and anaphylaxis are similar in general, but some peculiarities can be observed. The diagnostic approach may differ, accordingly to the condition, suspicious causes, age groups and regions. Adrenaline is the first-line treatment for anaphylaxis, but not for acute urticaria, where H1-antihistamines are the first choice. In this paper, we review the main aspects, similarities and differences regarding definitions, mechanisms, causes, diagnosis and treatment of acute urticaria and anaphylaxis.
急性荨麻疹是一种常见疾病，表现为风团和/或血管性水肿。然而，这些症状在过敏反应中也很常见，过敏反应是一种危及生命的反应，应立即进行诊断和治疗。在这两种疾病中，肥大细胞在生理病理学中都起着核心作用。急性荨麻疹和过敏反应的病因和触发因素通常相似，但也有一些特殊之处。根据病情、可疑病因、年龄组和地区的不同，诊断方法可能会有所不同。肾上腺素是过敏反应的一线治疗药物，但不是急性荨麻疹的一线治疗药物，急性荨麻疹的首选治疗药物是H1抗组胺药。在本文中，我们回顾了急性荨麻疹和过敏反应在定义、机制、病因、诊断和治疗方面的主要方面、异同点。
