Dager William E, Gulseth Michael P
University of California (UC) Davis Medical Center, Sacramento, CA 95817-2201, USA.
Am J Health Syst Pharm. 2007 May 15;64(10):1071-9. doi: 10.2146/ajhp060133.
This article identifies approaches for implementing an inpatient anticoagulation program involving pharmacists; two successful inpatient anticoagulation programs previously reported in the literature are described with a discussion of steps to consider in developing or expanding such a service.
Two institutions implemented pharmacist-managed anticoagulation services. One institution identified an undesirable incidence of medication-related adverse events occurring in hospitalized patients receiving anticoagulants. Pharmacists were asked to assist. Pharmacist activities included the selection of anticoagulants, patient education, verification of insurance coverage of the patient's anticoagulant, and coordination of follow-up. Physicians were available to assist. At the other institution, the department of pharmacy was asked by the orthopedic surgeons to manage warfarin for the prophylaxis against venous thromboembolism. The pharmacy department worked with the medical staff to gain approval of all policies, guidelines, and protocols to establish an anticoagulation service. Because of the success of the program, the pharmacy department expanded the service beyond warfarin. The steps to establishment of an anticoagulation service are described. The challenges facing such programs are discussed, including the potential anticoagulants in development that will create ongoing challenges in deciding which anticoagulation approach to use and in identifying patients for whom the newer agents may or may not be best suited.
Requirements for establishing a successful inpatient anticoagulation management program included defining the pharmacist's role in identifying patient needs, gaining support from other health care professionals, designing a program that addresses the needs of the patients, and managing unanticipated issues.
本文确定了实施涉及药剂师的住院患者抗凝计划的方法;描述了先前文献中报道的两个成功的住院患者抗凝计划,并讨论了在开展或扩大此类服务时应考虑的步骤。
两家机构实施了由药剂师管理的抗凝服务。一家机构发现接受抗凝剂治疗的住院患者中发生药物相关不良事件的发生率不理想。于是请药剂师提供协助。药剂师的活动包括选择抗凝剂、患者教育、核实患者抗凝剂的保险覆盖范围以及协调随访。医生也随时提供协助。在另一家机构,骨科外科医生要求药房管理华法林以预防静脉血栓栓塞。药房与医务人员合作,获得了所有政策、指南和方案的批准,以建立抗凝服务。由于该计划的成功,药房将服务范围扩大到了华法林以外的药物。文中描述了建立抗凝服务的步骤。讨论了此类计划面临的挑战,包括正在研发的潜在抗凝剂,这将在决定使用哪种抗凝方法以及确定哪些患者最适合使用新型抗凝剂方面带来持续挑战。
建立成功的住院患者抗凝管理计划的要求包括明确药剂师在确定患者需求方面的作用、获得其他医疗保健专业人员的支持、设计一个满足患者需求的计划以及处理意外问题。