饮用水中微囊藻毒素的细菌降解消除了它们的毒性。
Bacterial degradation of microcystin toxins in drinking water eliminates their toxicity.
作者信息
Ho Lionel, Gaudieux Anne-Laure, Fanok Stella, Newcombe Gayle, Humpage Andrew R
机构信息
Cooperative Research Centre for Water Quality and Treatment, South Australian Water Corporation, PMB 3, Salisbury, SA 5108, Australia.
出版信息
Toxicon. 2007 Sep 1;50(3):438-41. doi: 10.1016/j.toxicon.2007.03.021. Epub 2007 Apr 11.
Microcystin-LR and -LA were readily biodegraded by a bacterium, Sphingpoyxis sp. LH21, in a treated reservoir water. Detection of the microcystins was conducted using high-performance liquid chromatography (HPLC), protein phosphatase 2A (PP2A) inhibition assay and a cell-based cytotoxicity assay. The HPLC results correlated well with the two assays. The decrease in cytotoxicity, coupled with the associated decrease in microcystin concentrations, indicated that no cytotoxic by-products were being generated, highlighting the applicability of biodegradation as a feasible treatment option for effective microcystin removal.
微囊藻毒素-LR和-LA在处理过的水库水中很容易被一种鞘氨醇单胞菌属细菌Sphingpoyxis sp. LH21生物降解。使用高效液相色谱法（HPLC）、蛋白磷酸酶2A（PP2A）抑制试验和基于细胞的细胞毒性试验对微囊藻毒素进行检测。HPLC结果与这两种试验结果相关性良好。细胞毒性的降低，以及微囊藻毒素浓度的相应降低，表明没有产生细胞毒性副产物，突出了生物降解作为有效去除微囊藻毒素的可行处理选项的适用性。
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