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妊娠20周前因胎盘早剥导致阴道出血,继而发生弥散性血管内凝血,并在看似符合常规先兆流产标准后出现胎儿丢失:一例病例报告及文献简要综述

Vaginal bleeding before 20 weeks gestation due to placental abruption leading to disseminated intravascular coagulation and fetal loss after appearing to satisfy criteria for routine threatened abortion: a case report and brief review of the literature.

作者信息

Hodgson Danner T, Lotfipour Shahram, Fox J Christian

机构信息

Department of Emergency Medicine, University of California-Irvine School of Medicine, Irvine, California, USA.

出版信息

J Emerg Med. 2007 May;32(4):387-92. doi: 10.1016/j.jemermed.2006.08.018. Epub 2007 Apr 12.

DOI:10.1016/j.jemermed.2006.08.018
PMID:17499692
Abstract

We present a case of placental abruption with concomitant disseminated intravascular coagulation in a woman who presented with vaginal bleeding. A 32-year-old pregnant woman at 17 and 4/7 weeks gestation with a 1-month history of intermittent abdominal pain presented to our Emergency Department (ED) with 1 h of vaginal bleeding. Upon initial history, the patient reported that she was diagnosed with "blood behind the placenta" the day before and was discharged on pelvic precautions. An ED ultrasound confirmed the sub-amniotic hematoma with placental hematoma and a viable intrauterine fetus. A low fibrinogen level was suggested for disseminated intravascular coagulation and increasing hemorrhage necessitated dilation and evacuation and multiple units of blood products on an emergent basis. Only a few cases have been described in the literature demonstrating disseminated intravascular coagulation in patients at fewer than 20 weeks gestation with routine ultrasound findings of live intrauterine pregnancy and subchorionic hemorrhage.

摘要

我们报告一例胎盘早剥合并弥散性血管内凝血的病例,该患者表现为阴道出血。一名32岁、孕17周加4/7天的孕妇,有1个月间歇性腹痛病史,因1小时阴道出血就诊于我院急诊科。初步问诊时,患者报告前一天被诊断为“胎盘后出血”,并在采取盆腔防护措施后出院。急诊科超声检查证实有羊膜下血肿、胎盘血肿及存活的宫内胎儿。低纤维蛋白原水平提示弥散性血管内凝血,出血增加需要紧急进行扩张刮宫术并输注多单位血液制品。文献中仅描述了少数几例妊娠少于20周、经常规超声检查发现宫内妊娠存活且有绒毛膜下出血的患者发生弥散性血管内凝血的病例。

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引用本文的文献

1
A Case of Life-threatening Obstetrical Hemorrhage Secondary to Placental Abruption at 17 Weeks of Gestation.一例妊娠17周时胎盘早剥继发危及生命的产科出血病例。
Clin Pract. 2014 Mar 27;4(1):605. doi: 10.4081/cp.2014.605.