“晶态右美沙芬”：游离碱右美沙芬。

"Crystal dex:" free-base dextromethorphan.

作者信息

Hendrickson Robert G, Cloutier Robert L

机构信息

Department of Emergency Medicine, Oregon Health & Science University, Portland, Oregon 97201-3098, USA.

出版信息

J Emerg Med. 2007 May;32(4):393-6. doi: 10.1016/j.jemermed.2007.03.010. Epub 2007 Apr 16.

DOI:10.1016/j.jemermed.2007.03.010

PMID:17499693

Abstract

Dextromethorphan (DXM) is a common component of combination cold medications that has become a popular drug of abuse for young adults. Abusers of DXM have developed a simple acid-base extraction technique to "free-base," or extract, the DXM from the unwanted guaifenesin, coloring agents, sweeteners, and alcohol that are typically included in combination cold preparations. We report a case of DXM overdose after ingestion of this purified "Crystal Dex" and discuss the "Agent Lemon" and single-phase extraction techniques that are used to free-base the dextromethorphan.

摘要

右美沙芬（DXM）是复方感冒药中的常见成分，已成为年轻人滥用的热门药物。DXM滥用者开发了一种简单的酸碱萃取技术，从复方感冒制剂中通常含有的不需要的愈创甘油醚、着色剂、甜味剂和酒精中“游离碱化”或提取出DXM。我们报告了一例因摄入这种纯化的“水晶右美沙芬”导致DXM过量的病例，并讨论了用于使右美沙芬游离碱化的“柠檬剂”和单相萃取技术。