Izmirly Peter M, Rivera Tania L, Buyon Jill P
Department of Medicine, Division of Rheumatology, New York University School of Medicine, 560 First Avenue, TCH-407, New York, NY 10016, USA.
Rheum Dis Clin North Am. 2007 May;33(2):267-85, vi. doi: 10.1016/j.rdc.2007.02.005.
Neonatal lupus has become an important model of passively acquired autoimmunity since the seminal observation in the late 1970s that sera from nearly all mothers of children with isolated congenital heart block (CHB) contain specific autoantibodies.
自20世纪70年代末的开创性观察发现,几乎所有患有孤立性先天性心脏传导阻滞(CHB)患儿的母亲血清中都含有特异性自身抗体以来,新生儿狼疮已成为被动获得性自身免疫的重要模型。