Sashidhar R B, Ramakrishna Y, Ramnath T, Bhat R V
National Institute of Nutrition, Indian Council of Medical Research, Hyderabad, India.
Trop Geogr Med. 1991 Jan-Apr;43(1-2):165-70.
Traditionally, the disease pellagra has been associated with corn consumption and niacin deficiency, and has presently been recognised as a multiple factor nutritional syndrome. In the recent past, it has been suggested that consumption of mycotoxin contaminated sorghum/corn may be involved in the development of pellagra in a sorghum/corn eating population. The present study relates to the assessment of levels of mycotoxins (aflatoxin B1 and T-2 toxin) in sorghum collected from a traditionally sorghum eating population. Despite 25% fungal contamination in the sorghum samples collected, the levels of mycotoxins were minimal (1.4%) and there was no incidence of pellagra in the survey area. The absence of pellagra in the survey areas may be attributed to the changing dietary pattern.
传统上，糙皮病一直与食用玉米和烟酸缺乏有关，目前已被认定为一种多因素营养综合征。最近，有人提出食用受霉菌毒素污染的高粱/玉米可能与以高粱/玉米为食的人群中糙皮病的发生有关。本研究涉及对从传统食用高粱的人群中采集的高粱中霉菌毒素（黄曲霉毒素B1和T-2毒素）水平的评估。尽管采集的高粱样本中有25%受到真菌污染，但霉菌毒素水平极低（1.4%），且调查区域内没有糙皮病发病情况。调查区域内没有糙皮病可能归因于饮食模式的改变。
