Baqui A H, Yunus M D, Zaman K, Mitra A K, Hossain K M
International Centre for Diarrhoeal Disease Research, Bangladesh, (ICDDR,B) Dhaka.
Trop Geogr Med. 1991 Jan-Apr;43(1-2):17-22.
In May 1983, a surveillance system was set up at a rural diarrhoea treatment centre of the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B) to study a 20% systematic sample of all admissions. Between May 1983 and April 1984, 2,635 patients were studied. A recognized enteric pathogen was detected in 69% of the patients screened, 15% of whom had a mixed infection. Vibrio cholerae 0: 1 was the most common enteropathogen detected (39%), followed by enterotoxigenic Escherichia coli (ETEC) (14%), Shigella spp. (11%), and Campylobacter jejuni (11%). Detection of C. jejuni was highest in infants, Shigella spp. in children between 1-4 years and V. cholerae 0:1 in children between 3-9 years of age. 75% of patients presented with watery diarrhoea, a presentation that was significantly more common in patients infected with V. cholerae 0:1 (94%) and ETEC (88%). Bloody diarrhoea was the presenting complaint in 18% of all patients, but in 65% of patients in whom Shigella spp. was isolated. Although 91% of patients reported that they had prior experience of use of oral rehydration therapy (ORT), 54% of the patients came to the treatment centre with no or mild dehydration and more than half of them did not use ORT before coming to the treatment centre. Most of these patients could have been safely treated at home if ORT could be made available and acceptable.
1983年5月，在孟加拉国腹泻病研究国际中心（ICDDR，B）的一个农村腹泻治疗中心建立了一个监测系统，以研究所有入院患者的20%系统样本。1983年5月至1984年4月，对2635名患者进行了研究。在筛查的患者中，69%检测到一种公认的肠道病原体，其中15%有混合感染。霍乱弧菌0:1是检测到的最常见肠道病原体（39%），其次是产肠毒素大肠杆菌（ETEC）（14%）、志贺菌属（11%）和空肠弯曲菌（11%）。空肠弯曲菌在婴儿中的检出率最高，志贺菌属在1至4岁儿童中最高，霍乱弧菌0:1在3至9岁儿童中最高。75%的患者表现为水样腹泻，这种表现在感染霍乱弧菌0:1（94%）和ETEC（88%）的患者中明显更常见。血性腹泻是所有患者中18%的主诉，但在分离出志贺菌属的患者中占65%。尽管91%的患者报告他们以前有口服补液疗法（ORT）的使用经验，但54%的患者到治疗中心时没有或只有轻度脱水，其中一半以上在来治疗中心之前没有使用ORT。如果ORT能够获得并被接受，这些患者中的大多数本可以在家中得到安全治疗。
