Rahman A S, Bari A, Molla A M
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka.
Trop Geogr Med. 1991 Jan-Apr;43(1-2):23-7.
In rural Bangladesh, standard glucose based oral rehydration salt (glucose-ORS) and rice based oral rehydration salt (rice-ORS) were compared as domiciliary treatment for watery diarrhoea. Using identical supply systems, packaged glucose-ORS was provided in one area and packets of rice-ORS in another. Mothers of under-five children in each area were trained in the preparation and use of the respective ORS. A third area, where no ORS was provided from the study source, served as comparison. In two years of surveillance and follow-up about 10,000 diarrhoeal episodes were detected in each area, approximately one-third of which were watery diarrhoea. Rice-ORS alone was used to treat 74% of these episodes and glucose-ORS alone for 65% of the episodes in the respective areas. Drugs were the main treatment regimen used in the comparison area. Results of the study showed that rice-ORS treated episodes of watery diarrhoea ended with shorter duration (median duration 2 days vs. 4 days) and fewer hospitalisation (0.1% vs. 0.5%) compared to those treated with glucose-ORS. These differences were statistically significant. But, diarrhoeal mortality was unaffected by the use of either ORS under the study situation.
在孟加拉国农村地区,对标准葡萄糖口服补液盐(葡萄糖-ORS)和大米口服补液盐(大米-ORS)作为水样腹泻的家庭治疗方法进行了比较。使用相同的供应系统,在一个地区提供包装好的葡萄糖-ORS,在另一个地区提供大米-ORS包。每个地区五岁以下儿童的母亲都接受了各自ORS制备和使用的培训。第三个地区未从研究来源提供ORS,作为对照。在两年的监测和随访中,每个地区检测到约10000例腹泻发作,其中约三分之一是水样腹泻。在各自地区,仅使用大米-ORS治疗了这些发作的74%,仅使用葡萄糖-ORS治疗了65%。药物是对照地区使用的主要治疗方案。研究结果表明,与使用葡萄糖-ORS治疗的水样腹泻发作相比,使用大米-ORS治疗的发作持续时间更短(中位持续时间2天对4天),住院人数更少(0.1%对0.5%)。这些差异具有统计学意义。但是,在研究情况下,腹泻死亡率不受使用任何一种ORS的影响。