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对德斯塔亚茨的回复,用酯交换脂肪替代反式脂肪。

Reply to Destaillats, interesterified fats to replace trans fat.

作者信息

Sundram Kalyana, Karupaiah Tilakavati, Hayes K C

出版信息

Nutr Metab (Lond). 2007 May 14;4:13. doi: 10.1186/1743-7075-4-13.

DOI:10.1186/1743-7075-4-13
PMID:17501991
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1872024/
Abstract

Although more sophisticated ways exist to analyze TG-MS than that applied in our study, the approach was able to identify the TG species sufficiently to emphasize the importance of TG structure. The criticism that differences in dietary fat saturation alone would explain the lipoprotein response across diets is not supported by careful scrutiny of the facts. Nor does fat saturation per se address the observed impact that fat structure had on insulin/glucose metabolism.

摘要

尽管存在比我们研究中所应用的方法更为复杂的甘油三酯-质谱分析法,但该方法能够充分识别甘油三酯种类,以强调甘油三酯结构的重要性。仅饮食脂肪饱和度差异就能解释不同饮食下脂蛋白反应的这种观点,经对事实的仔细审查后并不成立。脂肪饱和度本身也无法解释所观察到的脂肪结构对胰岛素/葡萄糖代谢的影响。

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1
Reply to Destaillats, interesterified fats to replace trans fat.对德斯塔亚茨的回复,用酯交换脂肪替代反式脂肪。
Nutr Metab (Lond). 2007 May 14;4:13. doi: 10.1186/1743-7075-4-13.
2
Replacing trans fat: the argument for palm oil with a cautionary note on interesterification.用反式脂肪酸替代物:棕榈油与酯交换的争论及警示。
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3
Maternal intake of trans-unsaturated or interesterified fatty acids during pregnancy and lactation modifies mitochondrial bioenergetics in the liver of adult offspring in mice.孕期和哺乳期母体摄入反式不饱和脂肪酸或酯交换脂肪酸会改变成年子代小鼠肝脏中的线粒体生物能量学。
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4
Interesterified Palm Olein (IEPalm) and Interesterified Stearic Acid-Rich Fat Blend (IEStear) Have No Adverse Effects on Insulin Resistance: A Randomized Control Trial.反式棕榈油(IEPalm)和富含反式硬脂酸的脂肪混合物(IEStear)对胰岛素抵抗无不良影响:一项随机对照试验。
Nutrients. 2018 Aug 17;10(8):1112. doi: 10.3390/nu10081112.
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Interesterified fat or palm oil as substitutes for partially hydrogenated fat in maternal diet can predispose obesity in adult male offspring.在母体饮食中用交酯化脂肪或棕榈油代替部分氢化脂肪可能会使成年雄性后代易患肥胖症。
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Interesterified Fats Induce Deleterious Effects on Adipose Tissue and Liver in LDLr-KO Mice.交联脂肪在 LDLr-KO 小鼠的脂肪组织和肝脏中产生有害影响。
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Effects of glucagon and insulin on plasma glucose, triglyceride, and triglyceride-rich lipoprotein concentrations in laying hens fed diets containing different types of fats.胰高血糖素和胰岛素对饲喂含不同类型脂肪日粮的蛋鸡血浆葡萄糖、甘油三酯和富含甘油三酯脂蛋白浓度的影响。
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本文引用的文献

1
Letter to the editor: healthy alternatives to trans fats.致编辑的信:反式脂肪的健康替代品
Nutr Metab (Lond). 2007 Apr 27;4:10. doi: 10.1186/1743-7075-4-10.
2
Stearic acid-rich interesterified fat and trans-rich fat raise the LDL/HDL ratio and plasma glucose relative to palm olein in humans.与棕榈油精相比,富含硬脂酸的酯交换脂肪和富含反式脂肪酸的脂肪会提高人体的低密度脂蛋白/高密度脂蛋白比率和血糖水平。
Nutr Metab (Lond). 2007 Jan 15;4:3. doi: 10.1186/1743-7075-4-3.
3
Small differences in the effects of stearic acid, oleic acid, and linoleic acid on the serum lipoprotein profile of humans.硬脂酸、油酸和亚油酸对人体血清脂蛋白谱影响的微小差异。
Am J Clin Nutr. 2005 Sep;82(3):510-6. doi: 10.1093/ajcn.82.3.510.
4
Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials.膳食脂肪酸和碳水化合物对血清总胆固醇与高密度脂蛋白胆固醇比值以及血清脂质和载脂蛋白的影响:60项对照试验的荟萃分析
Am J Clin Nutr. 2003 May;77(5):1146-55. doi: 10.1093/ajcn/77.5.1146.
5
Dietary fatty acid thresholds and cholesterolemia.膳食脂肪酸阈值与胆固醇血症
FASEB J. 1992 May;6(8):2600-7. doi: 10.1096/fasebj.6.8.1592210.