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[中间型过敏中肺泡表面活性物质的物理化学性质]

[Physico-chemical properties of alveolar surfactant in intermediate type allergy].

作者信息

Bashmakov Iu K, Kholin S E, Briuzgina T S

出版信息

Vopr Med Khim. 1991 Jul-Aug;37(4):74-6.

PMID:1750217
Abstract

Development of sensitization involved accumulation of protein, lipoproteins and neutral triglycerides in lung surfactant, which inactivated surface active phospholipids and decreased the surface activity of surfactant. In anaphylactic shock a decrease in content of phospholipids and alteration of their fatty acid spectrum occurred as a result of which the moistening capacity of the covering complex was lowered and expiration of the bronchoalveolar secretion was restricted thus contributing to formation of asphyxia.

摘要

致敏作用的发展涉及肺表面活性物质中蛋白质、脂蛋白和中性甘油三酯的积累,这使表面活性磷脂失活并降低了表面活性物质的表面活性。在过敏性休克中,磷脂含量降低及其脂肪酸谱发生改变,结果覆盖复合物的湿润能力降低,支气管肺泡分泌物的排出受到限制,从而导致窒息的形成。

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1
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