Bashmakov Iu K, Kholin S E, Briuzgina T S
Vopr Med Khim. 1991 Jul-Aug;37(4):74-6.
Development of sensitization involved accumulation of protein, lipoproteins and neutral triglycerides in lung surfactant, which inactivated surface active phospholipids and decreased the surface activity of surfactant. In anaphylactic shock a decrease in content of phospholipids and alteration of their fatty acid spectrum occurred as a result of which the moistening capacity of the covering complex was lowered and expiration of the bronchoalveolar secretion was restricted thus contributing to formation of asphyxia.
致敏作用的发展涉及肺表面活性物质中蛋白质、脂蛋白和中性甘油三酯的积累,这使表面活性磷脂失活并降低了表面活性物质的表面活性。在过敏性休克中,磷脂含量降低及其脂肪酸谱发生改变,结果覆盖复合物的湿润能力降低,支气管肺泡分泌物的排出受到限制,从而导致窒息的形成。