Radhakrishnan Anant, Drobatz Kenneth J, Culp William T N, King Lesley G
Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
J Am Vet Med Assoc. 2007 May 15;230(10):1493-7. doi: 10.2460/javma.230.10.1493.
To identify causative organisms, treatment, outcome, and prognosis for dogs < 1 year old with community-acquired infectious pneumonia.
Retrospective case series.
65 dogs.
Dogs were considered to have community-acquired infectious pneumonia if they had clinical signs of primary respiratory tract disease in conjunction with radiographic evidence of alveolar disease and positive results following bacterial culture of tracheal wash fluid.
Most dogs were hypoxemic at the time of initial examination, with pulmonary function becoming worse during the first few days of hospitalization before improving; 57 (88%) dogs survived to discharge. Bordetella bronchiseptica was isolated from tracheal wash fluid from 32 (49%) dogs, and other organisms, predominantly gram-negative enteric bacteria, were isolated from the other 33 (51%). Dogs with Bordetella pneumonia were significantly younger (median, 14 vs 21 weeks), were significantly more likely to have been obtained from a pet store (19/31 vs 7/32), had been owned for a significantly shorter time prior to the onset of illness (median, 18 vs 90 days), had significantly higher PvCO2 values at initial examination (median, 48.7 vs 41.3 mm Hg), were significantly more likely to receive supplemental oxygen (25/32 vs 16/33), and had significantly longer hospitalization times (mean, 7.2 vs 4.9 days) than did dogs with pneumonia caused by any other organism.
Results suggested that a type of community-acquired infectious pneumonia could be identified in dogs < 1 year old, with disease being more severe in dogs with Bordetella pneumonia than in dogs with pneumonia caused by other bacterial organisms.
确定1岁以下社区获得性感染性肺炎犬的病原体、治疗方法、转归及预后。
回顾性病例系列研究。
65只犬。
若犬出现原发性呼吸道疾病的临床症状，同时伴有肺泡疾病的影像学证据以及气管冲洗液细菌培养呈阳性结果，则被认为患有社区获得性感染性肺炎。
大多数犬在初次检查时存在低氧血症，肺功能在住院的头几天恶化，之后有所改善；57只（88%）犬存活至出院。从32只（49%）犬的气管冲洗液中分离出支气管败血博德特氏菌，从另外33只（51%）犬中分离出其他病原体，主要是革兰氏阴性肠道细菌。患有博德特氏菌肺炎的犬明显更年轻（中位数为14周对21周），从宠物店获得的可能性显著更高（19/31对7/32），发病前拥有的时间显著更短（中位数为18天对90天），初次检查时的PvCO2值显著更高（中位数为48.7对41.3 mmHg），接受补充氧气的可能性显著更高（25/32对16/33），住院时间显著更长（平均为7.2天对4.9天），比由其他任何病原体引起肺炎的犬都要长。
结果表明，1岁以下的犬中可识别出一种社区获得性感染性肺炎，博德特氏菌肺炎犬的病情比其他细菌病原体引起肺炎的犬更严重。
