Chua Kaw Yan, Cheong Nge, Kuo I-Chun, Lee Bee Wah, Yi Fong Cheng, Huang Chiung-Hui, Liew Lip Nyin
Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Protein Pept Lett. 2007;14(4):325-33. doi: 10.2174/092986607780363862.
Blomia tropicalis allergens are the most important mite allergens in tropical regions. Most of them only have 30-40% sequence identity with their Dermatophagoides counterparts and they share low IgE cross reactivity and exhibit different immunobiology. Unlike the pyroglyphid counterparts, Blo t 5 is the major allergen whereas Blo t 1 only has modest allergenicity.
热带无爪螨变应原是热带地区最重要的螨类变应原。它们中的大多数与尘螨属对应物的序列同一性仅为30%-40%，并且它们具有较低的IgE交叉反应性，表现出不同的免疫生物学特性。与粉尘螨属对应物不同，热带无爪螨5是主要变应原，而热带无爪螨1的变应原性较弱。
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