Rautio M, Sipponen A, Peltola R, Lohi J, Jokinen J J, Papp A, Carlson P, Sipponen P
Division of Clinical Microbiology, HUSLAB, Helsinki University Hospital, Jorvi Hospital, Espoo, Finland.
APMIS. 2007 Apr;115(4):335-40. doi: 10.1111/j.1600-0463.2007.apm_548.x.
Resin salve made from Norway spruce (Picea abies) is traditionally used in folk medicine to heal skin ulcers and infected wounds. Its antimicrobial properties were studied against certain human bacteria important in infected skin wounds. The sensitivity of the resin against Gram-positive and Gram-negative bacteria was studied in vitro by methods that are routinely used in microbiology laboratories. The resin salve exhibited a bacteriostatic effect against all tested Gram-positive bacteria but only against Proteus vulgaris of the Gram-negative bacteria. Interestingly, the resin inhibited the growth of bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococcus (VRE), both on agar plates and in culture media. The study demonstrated antimicrobial activity of the resin salve and provided objective evidence of its antimicrobial properties. It gives some explanations why the traditional use of home-made resin salve from Norway spruce is experienced as being effective in the treatment of infected skin ulcers.
由挪威云杉(Picea abies)制成的树脂药膏传统上用于民间医学,以治疗皮肤溃疡和感染伤口。研究了其对感染皮肤伤口中某些重要人类细菌的抗菌特性。通过微生物实验室常规使用的方法,在体外研究了该树脂对革兰氏阳性菌和革兰氏阴性菌的敏感性。该树脂药膏对所有测试的革兰氏阳性菌均表现出抑菌作用,但仅对革兰氏阴性菌中的普通变形杆菌有抑菌作用。有趣的是,该树脂在琼脂平板和培养基中均能抑制包括耐甲氧西林金黄色葡萄球菌(MRSA)和耐万古霉素肠球菌(VRE)在内的细菌生长。该研究证明了树脂药膏的抗菌活性,并为其抗菌特性提供了客观证据。这为为什么传统上使用自制的挪威云杉树脂药膏治疗感染性皮肤溃疡有效提供了一些解释。