Kasenga F, Hurtig A-K, Emmelin M
Malamulo SDA Hospital, Makwasa, Malawi.
AIDS Care. 2007 May;19(5):646-52. doi: 10.1080/09540120701235651.
Although nevirapine (NVP) is provided by prevention of mother-to-child-transmission (PMTCT) of HIV programmes to be taken at onset of labor independent of place of delivery, few studies have assessed adherence to NVP outside the hospital setting. This study aimed to follow women in a PMTCT programme up to delivery and to assess the adherence to the prophylaxis in rural Malawi. A total of 75 HIV-positive women were registered in the PMTCT at Malamulo SDA hospital between January and June 2005. Forty women (53%) delivered in the hospital and 35 (47%) did not. Of the 35 women who delivered at home, it was possible to trace 27 (77.2%). All women who delivered in the hospital took their NVP tablets and all their babies had NVP syrup except one baby who died soon after delivery. Of the 27 traced women who had not delivered in the hospital, 16 (59.3%) had access to NVP and had taken their tablets during labor. However, none of their babies was taken back to the health facility for NVP syrup. Traditional birth attendants might be crucial in efforts aiming to increase adherence to NVP among women and their babies.
尽管在预防母婴传播(PMTCT)项目中,奈韦拉平(NVP)是在临产前提供的,无论分娩地点在哪里,但很少有研究评估在医院环境之外对NVP的依从性。本研究旨在追踪参与PMTCT项目的女性直至分娩,并评估马拉维农村地区对该预防措施的依从性。2005年1月至6月期间,共有75名HIV阳性女性在马拉穆洛基督复临安息日会医院登记参加PMTCT项目。40名女性(53%)在医院分娩,35名(47%)没有在医院分娩。在35名在家分娩的女性中,能够追踪到27名(77.2%)。所有在医院分娩的女性都服用了NVP片剂,除了一名婴儿在分娩后不久死亡外,她们所有的婴儿都服用了NVP糖浆。在27名追踪到的未在医院分娩的女性中,16名(59.3%)能够获得NVP并在分娩时服用了片剂。然而,她们的婴儿没有一个被带回医疗机构服用NVP糖浆。传统助产士对于提高女性及其婴儿对NVP的依从性的努力可能至关重要。