Brunon J, Nuti C
Service de neurochirurgie, hôpital de Bellevue, CHU de Saint-Etienne, 17 boulevard Pasteur, 42055 Saint-Etienne cedex 02, France.
Neurochirurgie. 2007 Jun;53(2-3 Pt 2):256-61. doi: 10.1016/j.neuchi.2007.03.010.
In this chapter we report the results of the main papers of the international literature, but it is difficult to make an objective synopsis because only the best results are published and failure and complications remain confidential. Few papers describe "general complications" as thrombo phlebitis, wound infection, cardio respiratory insufficiency... which are probably as frequent as for all intracranial or spinal surgical procedures. The postoperative neurological status depends essentially on the location of the lesion. In non eloquent area, the postoperative neurological status is almost always excellent. But in a hemispheric functional area, basal ganglia and brain stem it is frequent to observe neurological sequellae; in the better series of the literature, 80% of the patients achieve a good outcome equivalent to or better than before the operation, but 20% are worsened. It is important to remember this fact before discussing the surgical indication. The risk of hemorrhage disappears after total surgical resection; and it is one of the benefits of the treatment, but this objective can be reached only when the lesion is unique. The risk persists in multiple forms and "de novo" cavernomas are always possible especially in familial forms. The main benefit is the treatment of epilepsy for seizure control. In case of good concordance between the location of the cavernoma and the clinical and electrical data, lesionectomy alone or lesionectomy with resection of the perilesional hemosiderin ring provide good results. In the event of severe epilepsy without good concordance between the site of the cavernoma and symptoms, the surgical approach may be functional and outcome less satisfactory.
在本章中,我们报告了国际文献中主要论文的结果,但由于仅发表了最佳结果,而失败和并发症仍属保密信息,因此很难做出客观的综述。很少有论文描述“一般并发症”,如血栓性静脉炎、伤口感染、心肺功能不全……这些并发症可能与所有颅内或脊柱外科手术的发生率一样高。术后神经状态主要取决于病变的位置。在非功能区,术后神经状态几乎总是很好。但在半球功能区、基底神经节和脑干,经常会观察到神经后遗症;在文献中较好的系列报道中,80%的患者术后效果良好,等同于或优于手术前,但有20%的患者病情恶化。在讨论手术指征之前,记住这一事实很重要。全切除术后出血风险消失;这是治疗的益处之一,但只有在病变单一的情况下才能实现这一目标。风险以多种形式存在,“新发”海绵状血管瘤总是有可能出现,尤其是在家族性病例中。主要益处是治疗癫痫以控制发作。如果海绵状血管瘤的位置与临床和电生理数据高度吻合,单纯病变切除术或切除病变周围含铁血黄素环的病变切除术可取得良好效果。如果癫痫严重且海绵状血管瘤位置与症状之间吻合不佳,手术方式可能需要采用功能性手术,效果可能不太理想。