Ng P C, Brownlee K G, Dear P R
Department of Paediatrics and Child Health, St Jame's University Hospital, Leeds.
Arch Dis Child. 1991 Oct;66(10 Spec No):1164-6. doi: 10.1136/adc.66.10_spec_no.1164.
Three cases of gastroduodenal perforation and one case of ulceration and extreme thinning of the gastric wall occurred in preterm babies treated with dexamethasone for bronchopulmonary dysplasia. This complication of treatment with steroids has not to our knowledge previously been described in preterm infants. Urgent abdominal paracentesis was an essential part of the resuscitation in these cases, and this potentially serious side effect should be considered in all babies treated with steroids.
在接受地塞米松治疗支气管肺发育不良的早产儿中，发生了3例胃十二指肠穿孔和1例胃壁溃疡并极度变薄的情况。据我们所知，这种类固醇治疗的并发症此前尚未在早产儿中被描述过。紧急腹腔穿刺术是这些病例复苏的重要组成部分，在所有接受类固醇治疗的婴儿中都应考虑这种潜在的严重副作用。
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