Trattnig Siegfried, Mamisch Tallal C, Welsch Goetz H, Glaser Christian, Szomolanyi Pavol, Gebetsroither Simone, Stastny Oliver, Horger Wilhelm, Millington Steven, Marlovits Stefan
MR Center, Department of Radiology, Medical University of Vienna, Vienna, Austria.
Invest Radiol. 2007 Jun;42(6):442-8. doi: 10.1097/01.rli.0000262088.67368.49.
To evaluate magnetic resonance (MR) T2 mapping for characterization of cartilage repair tissue following matrix-associated autologous cartilage transplantation (MACT).
Fifteen patients were evaluated following MACT using a 3T MR scanner. Patients were categorized into 2 postoperative intervals: I: 3-13 months, II: 19-42 months. Mean T2 relaxation times calculated from multiple spin-echo sequence were determined in regions of interest (MACT and normal hyaline cartilage) and T2 line profiles through the repair tissue and control sites were acquired.
Mean global T2 values of repair tissue in group I were significantly higher than at control sites (P < 0.05). Repair tissue in group II showed no significant difference to control sites. Repair tissue T2 line profiles normalized over time toward the control sites.
T2 mapping allows visualization of cartilage repair tissue maturation. Global T2 repair tissue values approach that of control sites after more than 1.5 years, similar behavior is seen in the zonal organization.
评估磁共振（MR）T2 成像在基质相关自体软骨移植（MACT）后软骨修复组织特征分析中的应用。
使用 3T MR 扫描仪对 15 例接受 MACT 的患者进行评估。患者被分为两个术后时间段：I：3 - 13 个月，II：19 - 42 个月。在感兴趣区域（MACT 组织和正常透明软骨）测定由多个自旋回波序列计算得出的平均 T2 弛豫时间，并获取通过修复组织和对照部位的 T2 线轮廓。
I 组修复组织的平均整体 T2 值显著高于对照部位（P < 0.05）。II 组修复组织与对照部位无显著差异。修复组织的 T2 线轮廓随时间向对照部位归一化。
T2 成像能够显示软骨修复组织的成熟情况。超过 1.5 年后，修复组织的整体 T2 值接近对照部位，在分层结构中也观察到类似表现。
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