Thomer Amanda J, Santoro Beer Kari A
Department of Clinical Studies-Philadelphia, Matthew J. Ryan Veterinary Hospital of the University of Pennsylvania, Michigan State University College of Veterinary Medicine, Philadelphia, PA, 19104 (Thomer), East Lansing, MI, 48824 (Santoro Beer).
J Vet Emerg Crit Care (San Antonio). 2018 Nov;28(6):573-578. doi: 10.1111/vec.12774. Epub 2018 Oct 7.
To describe 4 cases of tracheal narrowing attributed to tracheal mucosal hemorrhage caused by anticoagulant rodenticide toxicity in breeds predisposed to tracheal collapse.
Over the years 2005-2014, 4 dogs were presented for respiratory distress secondary to diffuse tracheal narrowing. All dogs had possible anticoagulant rodenticide ingestion and prolonged prothrombin time. All dogs received fresh-frozen plasma transfusions, vitamin K supplementation, and supportive care. Tracheal narrowing improved on follow-up radiographs in 3 of 4 patients. One of 4 did not have follow-up radiographs performed. All dogs survived.
Anticoagulant rodenticide toxicity causing clinical signs consistent with tracheal collapse is a rare but recognized phenomenon that has not been previously reported in breeds prone to tracheal collapse.
描述4例因抗凝血灭鼠剂中毒导致气管黏膜出血而引起气管狭窄的病例，这些病例发生于易患气管塌陷的犬种。
在2005年至2014年期间，4只犬因弥漫性气管狭窄继发呼吸窘迫前来就诊。所有犬均可能摄入了抗凝血灭鼠剂，且凝血酶原时间延长。所有犬均接受了新鲜冷冻血浆输注、维生素K补充及支持性治疗。4例患者中有3例在随访X光片上显示气管狭窄有所改善。4例中有1例未进行随访X光检查。所有犬均存活。
抗凝血灭鼠剂中毒导致与气管塌陷一致的临床症状是一种罕见但已被认识到的现象，此前在易患气管塌陷的犬种中尚未见报道。
