Thoms Susan S, Musch David C, Soong H Kaz
Department of Ophthalmology and Visual Sciences, Medical School, University of Michigan, Ann Arbor, Michigan 48152, USA.
Br J Ophthalmol. 2007 Jun;91(6):728-30. doi: 10.1136/bjo.2006.109827.
To compare the incidence of postoperative endophthalmitis in clear corneal cataract surgeries performed with and without suture closure, antibiotics and povidone iodine.
Ambulatory surgery facility.
In a retrospective, consecutive case-series study, we reviewed the incidence of endophthalmitis in 815 consecutive eyes that underwent cataract surgery by a single surgeon over a 5-year period (379 unsutured and 436 sutured, 294 without and 521 with antibiotic drops in the immediate postoperative period, and 247 without and 568 with povidone iodine before patching).
There were five cases of culture-positive postoperative endophthalmitis in the unsutured group and none in the sutured group (p = 0.022). Although patients in these two groups received routine preoperative antibiotic and povidone-iodine drops, those in whom antibiotic eye drops were not initiated until the day after surgery (p = 0.006) and those who did not receive 5% povidone-iodine drops immediately after wound closure (p = 0.031), had a higher incidence of endophthalmitis.
Results suggest that by suturing the corneal incisions, by initiating antibiotic eye drops within the first 24 h of surgery and by instilling povidone-iodine drops after closure, the incidence of endophthalmitis after cataract surgery could possibly be reduced.
比较在有或没有缝线闭合、使用抗生素和聚维酮碘的情况下进行透明角膜白内障手术的术后眼内炎发生率。
门诊手术机构。
在一项回顾性、连续性病例系列研究中,我们回顾了一位外科医生在5年期间连续进行白内障手术的815只眼中眼内炎的发生率(379只未缝合和436只缝合,294只术后即刻未使用抗生素滴眼液而521只使用,以及247只在包扎前未使用聚维酮碘而568只使用)。
未缝合组有5例培养阳性的术后眼内炎,缝合组无(p = 0.022)。尽管这两组患者术前均接受常规抗生素和聚维酮碘滴眼液治疗,但术后第一天才开始使用抗生素滴眼液的患者(p = 0.006)以及伤口闭合后未立即使用5%聚维酮碘滴眼液的患者(p = 0.031),眼内炎发生率更高。
结果表明,通过缝合角膜切口、在手术的头24小时内开始使用抗生素滴眼液以及在闭合后滴注聚维酮碘滴眼液,白内障手术后眼内炎的发生率可能会降低。