Bohigian G M
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Ophthalmic Surg Lasers. 1999 Apr;30(4):295-8.
To determine the incidence of culture-positive endophthalmitis after cataract surgery in an ambulatory surgical care center and to analyze the effectiveness of povidoneiodine solution in the preoperative preparation in preventing culture-positive endophthalmitis.
A retrospective series of 19,269 consecutive cases of cataract extraction with lens implantation over 12 years in an ambulatory care center was reviewed.
Nine cases of culture-positive endophthalmitis occurred, for an incidence of 0.05%. The initial 4,740 cases (1985-1989) were performed without the use of povidone-iodine; the following 14,529 cases (1990-1996) were done using povidone-iodine. The incidence of culture-positive endophthalmitis was 0.08% and 0.03%, respectively.
The incidence of culture-positive endophthalmitis in this series was very low. The use of 5% povidone-iodine, topically, appeared to be beneficial in reducing the incidence of culture-positive endophthalmitis after cataract extraction (P=0.24), but was not statistically significant in this retrospective series. Evaluation and methods to prevent endophthalmitis are difficult in retrospective clinical studies due to multiple variables and the rarity of this complication.
确定门诊手术护理中心白内障手术后培养阳性眼内炎的发生率,并分析聚维酮碘溶液在术前准备中预防培养阳性眼内炎的有效性。
回顾性分析了一家门诊护理中心12年间连续进行的19269例白内障摘除联合人工晶状体植入手术病例。
发生9例培养阳性眼内炎,发生率为0.05%。最初的4740例(1985 - 1989年)手术未使用聚维酮碘;随后的14529例(1990 - 1996年)手术使用了聚维酮碘。培养阳性眼内炎的发生率分别为0.08%和0.03%。
本系列中培养阳性眼内炎的发生率很低。局部使用5%聚维酮碘似乎有助于降低白内障摘除术后培养阳性眼内炎的发生率(P = 0.24),但在这个回顾性系列研究中无统计学意义。由于存在多个变量以及该并发症的罕见性,在回顾性临床研究中评估和预防眼内炎的方法具有难度。