Arving Cecilia, Sjödén Per-Olow, Bergh Jonas, Hellbom Maria, Johansson Birgitta, Glimelius Bengt, Brandberg Yvonne
Department of Public Health and Caring Sciences, Section of Caring Sciences, Uppsala University, Uppsala, Sweden.
Cancer Nurs. 2007 May-Jun;30(3):E10-9. doi: 10.1097/01.NCC.0000270709.64790.05.
In a prospective, randomized study, an individual psychosocial support intervention performed by specially trained oncology nurses, or psychologists, were compared with standard care. Consecutive primary breast cancer patients about to start adjuvant therapy (n = 179) were included. Data were supplied by the questionnaires European Organisation for Research and Treatment of Cancer Quality of Life Study Group Core Quality of life questionnaire with 30 questions (EORTC QLQ-C30) and Breast Cancer Module with 23 questions (BR23), the Hospital Anxiety and Depression Scale, Spielberger's State-Trait Anxiety Inventory, and the Impact of Event Scale before randomization and 1, 3, and 6 months later. Patient files provided data on utilization of psychosocial support offered in routine care. Global quality of life/health status, nausea and vomiting, and systemic therapy side effects were the subscales showing significant Group by Time interactions, favoring the interventions. Intervention groups improved statistically significantly more than the standard care group regarding insomnia, dyspnea, and financial difficulties. Nurse patients experienced less intrusion compared with the standard care group. All groups showed statistically and clinically significant improvements with time on several subscales. The intervention groups, however, improved to a greater extent. Fewer patients in the intervention groups used psychosocial hospital support compared with the standard care group. In conclusion, psychosocial support by specially trained nurses using techniques derived from cognitive behavioral therapy is beneficial for breast cancer patients and may be a realistic alternative in routine cancer care.
在一项前瞻性随机研究中,将由经过专门培训的肿瘤护士或心理学家实施的个体心理社会支持干预与标准护理进行了比较。纳入了即将开始辅助治疗的连续性原发性乳腺癌患者(n = 179)。数据通过问卷调查提供,包括欧洲癌症研究与治疗组织生活质量研究组核心生活质量问卷(30个问题,EORTC QLQ - C30)和乳腺癌模块(23个问题,BR23)、医院焦虑抑郁量表、斯皮尔伯格状态 - 特质焦虑量表以及随机分组前、1个月、3个月和6个月后的事件影响量表。患者档案提供了常规护理中提供的心理社会支持利用情况的数据。生活质量/健康状况总体评分、恶心和呕吐以及全身治疗副作用是显示出显著的组×时间交互作用的分量表,干预组更具优势。在失眠、呼吸困难和经济困难方面,干预组在统计学上的改善明显超过标准护理组。与标准护理组相比,护士干预组患者受到的侵扰更少。随着时间推移,所有组在几个分量表上均显示出统计学和临床上的显著改善。然而,干预组的改善程度更大。与标准护理组相比,干预组中使用心理社会医院支持的患者更少。总之,经过专门培训的护士采用认知行为疗法技术提供的心理社会支持对乳腺癌患者有益,可能是常规癌症护理中的一种切实可行的替代方案。